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Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses

Therapeutic gene transfer by replication-defective viral vectors or, for cancer treatment, by replication-competent oncolytic viruses shows high promise for treatment of major diseases. To ensure safety, timing or dosing in patients, external control of therapeutic gene expression is desirable or ev...

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Bibliographic Details
Main Authors: Ketzer, Patrick, Haas, Simon F., Engelhardt, Sarah, Hartig, Jörg S., Nettelbeck, Dirk M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505972/
https://ncbi.nlm.nih.gov/pubmed/22885302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks734
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