Braveheart, a long non-coding RNA required for cardiovascular lineage commitment

Long noncoding RNAs (lncRNAs) are often expressed in a development-specific manner, yet little is known about their roles in lineage commitment. Here, we identified Braveheart (Bvht), a heart-associated lncRNA in mouse. Using multiple embryonic stem cell (ESC) differentiation strategies, we show tha...

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Detalhes bibliográficos
Main Authors: Klattenhoff, Carla, Scheuermann, Johanna C., Surface, Lauren E., Bradley, Robert K., Fields, Paul A., Steinhauser, Matthew L., Ding, Huiming, Butty, Vincent L., Torrey, Lillian, Haas, Simon, Abo, Ryan, Tabebordbar, Mohammadsharif, Lee, Richard T., Burge, Christopher B., Boyer, Laurie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563769/
https://ncbi.nlm.nih.gov/pubmed/23352431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.01.003
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