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Braveheart, a long non-coding RNA required for cardiovascular lineage commitment

Long noncoding RNAs (lncRNAs) are often expressed in a development-specific manner, yet little is known about their roles in lineage commitment. Here, we identified Braveheart (Bvht), a heart-associated lncRNA in mouse. Using multiple embryonic stem cell (ESC) differentiation strategies, we show tha...

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Bibliographische Detailangaben
Hauptverfasser: Klattenhoff, Carla, Scheuermann, Johanna C., Surface, Lauren E., Bradley, Robert K., Fields, Paul A., Steinhauser, Matthew L., Ding, Huiming, Butty, Vincent L., Torrey, Lillian, Haas, Simon, Abo, Ryan, Tabebordbar, Mohammadsharif, Lee, Richard T., Burge, Christopher B., Boyer, Laurie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563769/
https://ncbi.nlm.nih.gov/pubmed/23352431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.01.003
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