Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease

Por Meredith Jr., Jere E., Sankaranarayanan, Sethu, Guss, Valerie, Lanzetti, Anthony J., Berisha, Flora, Neely, Robert J., Slemmon, J. Randall, Portelius, Erik, Zetterberg, Henrik, Blennow, Kaj, Soares, Holly, Ahlijanian, Michael, Albright, Charles F.
Publicado em 2013

Viable mouse gene ablations that robustly alter brain Aβ levels are rare

Por Small Daniel L, Majumdar Antara, Corradi John, Barrezueta Nestor, Sankaranarayanan Sethu, Meredith Jere E, Guss Valerie, Thompson Mark W, Lin Xu-Alan, Toyn Jeremy H, Hansard Melissa, Lanthorn Thomas, Westphal Ryan S, Albright Charles F
Publicado em 2010-11-01

Viable mouse gene ablations that robustly alter brain Aβ levels are rare

Por Toyn, Jeremy H, Lin, Xu-Alan, Thompson, Mark W, Guss, Valerie, Meredith, Jere E, Sankaranarayanan, Sethu, Barrezueta, Nestor, Corradi, John, Majumdar, Antara, Small, Daniel L, Hansard, Melissa, Lanthorn, Thomas, Westphal, Ryan S, Albright, Charles F
Publicado em 2010

Divergent CSF tau alterations in two common tauopathies: Alzheimer’s disease and Progressive Supranuclear Palsy

Por Wagshal, Dana, Sankaranarayanan, Sethu, Guss, Valerie, Hall, Tracey, Berisha, Flora, Lobach, Iryna, Karydas, Anna, Voltarelli, Lisa, Scherling, Carole, Heuer, Hilary, Tartaglia, Maria Carmela, Miller, Zachary, Coppola, Giovanni, Ahlijanian, Michael, Soares, Holly, Kramer, Joel H, Rabinovici, Gil D, Rosen, Howard J, Miller, Bruce L, Meredith, Jere, Boxer, Adam L
Publicado no J Neurol Neurosurg Psychiatry (2014)

Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects

Por Toyn, Jeremy H., Boy, Kenneth M., Raybon, Joseph, Meredith, Jere E., Robertson, Alan S., Guss, Valerie, Hoque, Nina, Sweeney, Francis, Zhuo, Xiaoliang, Clarke, Wendy, Snow, Kimberly, Denton, R. Rex, Zuev, Dmitry, Thompson, Lorin A., Morrison, John, Grace, James, Berisha, Flora, Furlong, Michael, Wang, Jun-Sheng, Lentz, Kimberly A., Padmanabha, Ramesh, Cook, Lynda, Wei, Cong, Drexler, Dieter M., Macor, John E., Albright, Charlie F., Gasior, Maciej, Olson, Richard E., Hong, Quan, Soares, Holly D., AbuTarif, Malaz, Ahlijanian, Michael K.
Publicado no J Pharmacol Exp Ther (2016)

Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780

Por Toyn, Jeremy H., Thompson, Lorin A., Lentz, Kimberley A., Meredith, Jere E., Burton, Catherine R., Sankaranararyanan, Sethu, Guss, Valerie, Hall, Tracey, Iben, Lawrence G., Krause, Carol M., Krause, Rudy, Lin, Xu-Alan, Pierdomenico, Maria, Polson, Craig, Robertson, Alan S., Denton, R. Rex, Grace, James E., Morrison, John, Raybon, Joseph, Zhuo, Xiaoliang, Snow, Kimberly, Padmanabha, Ramesh, Agler, Michele, Esposito, Kim, Harden, David, Prack, Margaret, Varma, Sam, Wong, Victoria, Zhu, Yingjie, Zvyaga, Tatyana, Gerritz, Samuel, Marcin, Lawrence R., Higgins, Mendi A., Shi, Jianliang, Wei, Cong, Cantone, Joseph L., Drexler, Dieter M., Macor, John E., Olson, Richard E., Ahlijanian, Michael K., Albright, Charles F.
Publicado em 2014