A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma

Por Yee, Karen S., Grochola, Lukasz, Hamilton, Garth, Grawenda, Anna, Bond, Elisabeth E., Taubert, Helge, Wurl, Peter, Bond, Gareth L., O’Neill, Eric
Publicado no Cancer Res (2012)

RASSF1A-LATS1 signalling stabilises replication forks by restricting CDK2-mediated phosphorylation of BRCA2

Por Pefani, Dafni-Eleftheria, Latusek, Robert, Pires, Isabel, Grawenda, Anna M., Yee, Karen S., Hamilton, Garth, van der Weyden, Louise, Esashi, Fumiko, Hammond, Ester M., O’Neill, Eric
Publicado no Nat Cell Biol (2014)

Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion

Por Vlahov, Nikola, Scrace, Simon, Soto, Manuel Sarmiento, Grawenda, Anna M., Bradley, Leanne, Pankova, Daniela, Papaspyropoulos, Angelos, Yee, Karen S., Buffa, Francesca, Goding, Colin R., Timpson, Paul, Sibson, Nicola, O’Neill, Eric
Publicado no Curr Biol (2015)

AKT regulates NPM dependent ARF localization and p53(mut) stability in tumors

Por Hamilton, Garth, Abraham, Aswin G., Morton, Jennifer, Sampson, Oliver, Pefani, Dafni E., Khoronenkova, Svetlana, Grawenda, Anna, Papaspyropoulos, Angelos, Jamieson, Nigel, McKay, Colin, Sansom, Owen, Dianov, Grigory L., O'Neill, Eric
Publicado em 2014

The importance of p53 pathway genetics in inherited and somatic cancer genomes

Por Stracquadanio, Giovanni, Wang, Xuting, Wallace, Marsha, Grawenda, Anna M., Zhang, Ping, Hewitt, Juliet, Zeron-Medina, Jorge, Castro-Giner, Francesc, Tomlinson, Ian P., Goding, Colin R., Cygan, Kamil J., Fairbrother, William G., Thomas, Laurent F., Sætrom, Pål, Gemignani, Frederica, Landi, Stefano, Schuster-Boeckler, Benjamin, Bell, Douglas A., Bond, Gareth L.
Publicado no Nat Rev Cancer (2016)

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73

Por Papaspyropoulos, Angelos, Bradley, Leanne, Thapa, Asmita, Leung, Chuen Yan, Toskas, Konstantinos, Koennig, Delia, Pefani, Dafni-Eleftheria, Raso, Cinzia, Grou, Claudia, Hamilton, Garth, Vlahov, Nikola, Grawenda, Anna, Haider, Syed, Chauhan, Jagat, Buti, Ludovico, Kanapin, Alexander, Lu, Xin, Buffa, Francesca, Dianov, Grigory, von Kriegsheim, Alex, Matallanas, David, Samsonova, Anastasia, Zernicka-Goetz, Magdalena, O’Neill, Eric
Publicado no Nat Commun (2018)