A Trisubstituted Benzimidazole Cell Division Inhibitor with Efficacy against Mycobacterium tuberculosis

per Knudson, Susan E., Awasthi, Divya, Kumar, Kunal, Carreau, Alexandra, Goullieux, Laurent, Lagrange, Sophie, Vermet, Hélèn, Ojima, Iwao, Slayden, Richard A.
Publicat 2014

Cell division inhibitors with efficacy equivalent to isoniazid in the acute murine Mycobacterium tuberculosis infection model

per Knudson, Susan E., Awasthi, Divya, Kumar, Kunal, Carreau, Alexandra, Goullieux, Laurent, Lagrange, Sophie, Vermet, Hélène, Ojima, Iwao, Slayden, Richard A.
Publicat a J Antimicrob Chemother (2015)

Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA

per Lopez Quezada, Landys, Silve, Sandra, Kelinske, Mark, Liba, Amir, Diaz Gonzalez, Constantino, Kotev, Martin, Goullieux, Laurent, Sans, Stephanie, Roubert, Christine, Lagrange, Sophie, Bacqué, Eric, Couturier, Cedric, Pellet, Alain, Blanc, Isabelle, Ferron, Marlène, Debu, Fabrice, Li, Kelin, Aubé, Jeffrey, Roberts, Julia, Little, David, Ling, Yan, Zhang, Jun, Gold, Ben, Nathan, Carl
Publicat a mBio (2019)

Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition

per Ballinger, Elaine, Mosior, John, Hartman, Travis, Burns-Huang, Kristin, Gold, Ben, Morris, Roxanne, Goullieux, Laurent, Blanc, Isabelle, Vaubourgeix, Julien, Lagrange, Sophie, Fraisse, Laurent, Sans, Stéphanie, Couturier, Cedric, Bacqué, Eric, Rhee, Kyu, Scarry, Sarah M., Aubé, Jeffrey, Yang, Guangbin, Ouerfelli, Ouathek, Schnappinger, Dirk, Ioerger, Thomas R., Engelhart, Curtis A., McConnell, Jennifer A., McAulay, Kathrine, Fay, Allison, Roubert, Christine, Sacchettini, James, Nathan, Carl
Publicat a Science (2019)

Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis

per Qpezada, Landys Lopez, Li, Kelin, McDonald, Stacey L., Nguyen, Quyen, Perkowski, Andrew J., Pharr, Cameron W., Gold, Ben, Roberts, Julia, McAulay, Kathrine, Saito, Kohta, Karakaya, Selin Somersan, Javidnia, Prisca Elis, de Francisco, Esther Porras, Amieva, Manuel Marin, Díaz, Sara Palomo, Losana, Alfonso Mendoza, Zimmerman, Matthew, Ho Liang, Hsin-Pin, Zhang, Jun, Dartois, Veronique, Sans, Stéphanie, Lagrange, Sophie, Goullieux, Laurent, Roubert, Christine, Nathan, Carl, Aubé, Jeffrey
Publicat a ACS Infect Dis (2019)