Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis

The historical view of β-lactams as ineffective antimycobacterials has given way to growing interest in the activity of this class against Mycobacterium tuberculosis (Mtb) in the presence of a β-lactamase inhibitor. However, most antimycobacterial β-lactams kill Mtb only or best when the bacilli are...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Qpezada, Landys Lopez, Li, Kelin, McDonald, Stacey L., Nguyen, Quyen, Perkowski, Andrew J., Pharr, Cameron W., Gold, Ben, Roberts, Julia, McAulay, Kathrine, Saito, Kohta, Karakaya, Selin Somersan, Javidnia, Prisca Elis, de Francisco, Esther Porras, Amieva, Manuel Marin, Díaz, Sara Palomo, Losana, Alfonso Mendoza, Zimmerman, Matthew, Ho Liang, Hsin-Pin, Zhang, Jun, Dartois, Veronique, Sans, Stéphanie, Lagrange, Sophie, Goullieux, Laurent, Roubert, Christine, Nathan, Carl, Aubé, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241432/
https://ncbi.nlm.nih.gov/pubmed/31184461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00112
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