Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis

[Image: see text] We report two series of novel cephalosporins that are bactericidal to Mycobacterium tuberculosis alone of the pathogens tested, which only kill M. tuberculosis when its replication is halted by conditions resembling those believed to pertain in the host, and whose bactericidal acti...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Gold, Ben, Smith, Robert, Nguyen, Quyen, Roberts, Julia, Ling, Yan, Lopez Quezada, Landys, Somersan, Selin, Warrier, Thulasi, Little, David, Pingle, Maneesh, Zhang, David, Ballinger, Elaine, Zimmerman, Matthew, Dartois, Véronique, Hanson, Paul, Mitscher, Lester A., Porubsky, Patrick, Rogers, Steven, Schoenen, Frank J., Nathan, Carl, Aubé, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947980/
https://ncbi.nlm.nih.gov/pubmed/27144688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01833
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