Inhibition of Phosphatidylinositol 3-Kinase Destabilizes Mycn Protein and Blocks Malignant Progression in Neuroblastoma

by Chesler, Louis, Schlieve, Chris, Goldenberg, David D., Kenney, Anna, Kim, Grace, McMillan, Alex, Matthay, Katherine K., Rowitch, David, Weiss, William A.
Published 2006

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

by Fan, Qi-Wen, Knight, Zachary A., Goldenberg, David D., Yu, Wei, Mostov, Keith E., Stokoe, David, Shokat, Kevan M., Weiss, William A.
Published 2006

Chemotherapy-Induced Apoptosis in a Transgenic Model of Neuroblastoma Proceeds Through p53 Induction

by Chesler, Louis, Goldenberg, David D, Collins, Rodney, Grimmer, Matt, Kim, Grace E, Tihan, Tarik, Nguyen, Kim, Yakovenko, Slava, Matthay, Katherine K, Weiss, William A
Published 2008

Nordihydroguaiaretic Acid Inhibits Insulin-Like Growth Factor Signaling, Growth, and Survival in Human Neuroblastoma Cells

by Meyer, Gary E., Chesler, Louis, Liu, Dandan, Gable, Karissa, Maddux, Betty A., Goldenberg, David D., Youngren, Jack F., Goldfine, Ira D., Weiss, William A., Matthay, Katherine K., Rosenthal, Stephen M.
Published 2007

Malignant Progression and Blockade of Angiogenesis in a Murine Transgenic Model of Neuroblastoma

by Chesler, Louis, Goldenberg, David D., Seales, Isha T., Satchi-Fainaro, Ronit, Grimmer, Matt, Collins, Rodney, Struett, Chris, Nguyen, Kim N., Kim, Grace, Tihan, Tarik, Bao, Yun, Brekken, Rolf A., Bergers, Gabriele, Folkman, Judah, Weiss, William A.
Published 2007

A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

by Knight, Zachary A., Gonzalez, Beatriz, Feldman, Morri E., Zunder, Eli R., Goldenberg, David D., Williams, Olusegun, Loewith, Robbie, Stokoe, David, Balla, Andras, Toth, Balazs, Balla, Tamas, Weiss, William A., Williams, Roger L., Shokat, Kevan M.
Published 2006

Non-stem cell origin for oligodendroglioma

by Persson, Anders I., Petritsch, Claudia, Swartling, Fredrik J., Itsara, Melissa, Sim, Fraser J., Auvergne, Romane, Goldenberg, David D., Vandenberg, Scott R., Nguyen, Kim N., Yakovenko, Stanislava, Ayers-Ringler, Jennifer, Nishiyama, Akiko, Stallcup, William B., Berger, Mitchel S., Bergers, Gabriele, McKnight, Tracy R., Goldman, Steve A., Weiss, William A.
Published 2010

eQTL and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma

by Hackett, Christopher S., Quigley, David A., Wong, Robyn A., Chen, Justin, Cheng, Christine, Song, Young K., Wei, Jun S., Pawlikowska, Ludmila, Bao, Yun, Goldenberg, David D., Nguyen, Kim, Gustafson, W. Clay, Rallapalli, Sundari K., Cho, Yoon-Jae, Cook, James M., Kozlov, Serguei, Mao, Jian-Hua, Van Dyke, Terry, Kwok, Pui-Yan, Khan, Javed, Balmain, Allan, Fan, QiWen, Weiss, William A.
Published in Cell Rep (2014)

Pleiotropic role for MYCN in medulloblastoma

by Swartling, Fredrik J., Grimmer, Matthew R., Hackett, Christopher S., Northcott, Paul A., Fan, Qi-Wen, Goldenberg, David D., Lau, Jasmine, Masic, Selma, Nguyen, Kim, Yakovenko, Slava, Zhe, Xiao-Ning, Flynn Gilmer, Heather C., Collins, Rodney, Nagaoka, Mai, Phillips, Joanna J., Jenkins, Robert B., Tihan, Tarik, Vandenberg, Scott R., James, C. David, Tanaka, Kohichi, Taylor, Michael D., Weiss, William A., Chesler, Louis
Published 2010