eQTL and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma

The development of targeted therapeutics for neuroblastoma, the third most common tumor in children, has been limited by a poor understanding of growth signaling mechanisms unique to the peripheral nerve precursors from which tumors arise. In this study, we combined genetics with gene expression ana...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Hackett, Christopher S., Quigley, David A., Wong, Robyn A., Chen, Justin, Cheng, Christine, Song, Young K., Wei, Jun S., Pawlikowska, Ludmila, Bao, Yun, Goldenberg, David D., Nguyen, Kim, Gustafson, W. Clay, Rallapalli, Sundari K., Cho, Yoon-Jae, Cook, James M., Kozlov, Serguei, Mao, Jian-Hua, Van Dyke, Terry, Kwok, Pui-Yan, Khan, Javed, Balmain, Allan, Fan, QiWen, Weiss, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251494/
https://ncbi.nlm.nih.gov/pubmed/25437558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.046
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