CHAC1/MGC4504 Is a Novel Proapoptotic Component of the Unfolded Protein Response, Downstream of the ATF4-ATF3-CHOP Cascade

por Mungrue, Imran N., Pagnon, Joanne, Kohannim, Omid, Gargalovic, Peter S., Lusis, Aldons J.
Publicado 2009

ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response

por Oskolkova, Olga V., Afonyushkin, Taras, Leitner, Alexander, von Schlieffen, Elena, Gargalovic, Peter S., Lusis, Aldons J., Binder, Bernd R., Bochkov, Valery N.
Publicado 2008

Quantitative Trait Locus Mapping and Identification of Zhx2 as a Novel Regulator of Plasma Lipid Metabolism

por Gargalovic, Peter S., Erbilgin, Ayça, Kohannim, Omid, Pagnon, Joanne, Wang, Xuping, Castellani, Lawrence, LeBoeuf, Renee, Peterson, Martha L., Spear, Brett T., Lusis, Aldons J.
Publicado 2009

Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits

por Civelek, Mete, Hagopian, Raffi, Pan, Calvin, Che, Nam, Yang, Wen-pin, Kayne, Paul S., Saleem, Niyas K., Cederberg, Henna, Kuusisto, Johanna, Gargalovic, Peter S., Kirchgessner, Todd G., Laakso, Markku, Lusis, Aldons J.
Publicado 2013

Systems Genetics Analysis of Gene-by-Environment Interactions in Human Cells

por Romanoski, Casey E., Lee, Sangderk, Kim, Michelle J., Ingram-Drake, Leslie, Plaisier, Christopher L., Yordanova, Roumyana, Tilford, Charles, Guan, Bo, He, Aiqing, Gargalovic, Peter S., Kirchgessner, Todd G., Berliner, Judith A., Lusis, Aldons J.
Publicado 2010

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

por Gargalovic, Peter, Wong, Pancras, Onorato, Joelle, Finlay, Heather, Wang, Tao, Yan, Mujing, Crain, Earl, St-Onge, Stéphane, Héroux, Madeleine, Bouvier, Michel, Xu, Carrie, Chen, Xue-Qing, Generaux, Claudia, Lawrence, Michael, Wexler, Ruth, Gordon, David
Publicado en Circ Heart Fail (2021)

The genetic architecture of NAFLD among inbred strains of mice

por Hui, Simon T, Parks, Brian W, Org, Elin, Norheim, Frode, Che, Nam, Pan, Calvin, Castellani, Lawrence W, Charugundla, Sarada, Dirks, Darwin L, Psychogios, Nikolaos, Neuhaus, Isaac, Gerszten, Robert E, Kirchgessner, Todd, Gargalovic, Peter S, Lusis, Aldons J
Publicado en eLife (2015)

Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids

por Gargalovic, Peter S., Imura, Minori, Zhang, Bin, Gharavi, Nima M., Clark, Michael J., Pagnon, Joanne, Yang, Wen-Pin, He, Aiqing, Truong, Amy, Patel, Shilpa, Nelson, Stanley F., Horvath, Steve, Berliner, Judith A., Kirchgessner, Todd G., Lusis, Aldons J.
Publicado 2006

Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages

por Orozco, Luz D., Bennett, Brian J., Farber, Charles R., Ghazalpour, Anatole, Pan, Calvin, Che, Nam, Wen, Pingzi, Qi, Hong Xiu, Mutukulu, Adonisa, Siemers, Nathan, Neuhaus, Isaac, Yordanova, Roumyana, Gargalovic, Peter, Pellegrini, Matteo, Kirchgessner, Todd, Lusis, Aldons J.
Publicado 2012

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

por Bennett, Brian J., Davis, Richard C., Civelek, Mete, Orozco, Luz, Wu, Judy, Qi, Hannah, Pan, Calvin, Packard, René R. Sevag, Eskin, Eleazar, Yan, Mujing, Kirchgessner, Todd, Wang, Zeneng, Li, Xinmin, Gregory, Jill C., Hazen, Stanley L., Gargalovic, Peter S., Lusis, Aldons J.
Publicado en PLoS Genet (2015)

Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

por Bennett, Brian J., Davis, Richard C., Civelek, Mete, Orozco, Luz, Wu, Judy, Qi, Hannah, Pan, Calvin, Sevag Packard, René R., Eskin, Eleazar, Yan, Mujing, Kirchgessner, Todd, Wang, Zeneng, Li, Xinmin, Gregory, Jill C., Hazen, Stanley L., Gargalovic, Peter S., Lusis, Aldons J.
Publicado en PLoS Genet (2016)

P2Y(6) Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

por Garcia, Ricardo A., Yan, Mujing, Search, Debra, Zhang, Rongan, Carson, Nancy L., Ryan, Carol S., Smith-Monroy, Constance, Zheng, Joanna, Chen, Jian, Kong, Yan, Tang, Huaping, Hellings, Samuel E., Wardwell-Swanson, Judith, Dinchuk, Joseph E., Psaltis, George C., Gordon, David A., Glunz, Peter W., Gargalovic, Peter S.
Publicado en PLoS One (2014)

Genetic Architecture of Insulin Resistance in the Mouse

por Parks, Brian W., Sallam, Tamer, Mehrabian, Margarete, Psychogios, Nikolas, Hui, Simon T., Norheim, Frode, Castellani, Lawrence W., Rau, Christoph, Pan, Calvin, Phun, Jennifer, Zhou, Zhenqi, Yang, Wen-Pin, Neuhaus, Isaac, Gargalovic, Peter S., Kirchgessner, Todd G., Graham, Mark, Lee, Richard, Tontonoz, Peter, Gerszten, Robert E., Hevener, Andrea L., Lusis, Aldons J.
Publicado en Cell Metab (2015)

A high-resolution association mapping panel for the dissection of complex traits in mice

por Bennett, Brian J., Farber, Charles R., Orozco, Luz, Min Kang, Hyun, Ghazalpour, Anatole, Siemers, Nathan, Neubauer, Michael, Neuhaus, Isaac, Yordanova, Roumyana, Guan, Bo, Truong, Amy, Yang, Wen-pin, He, Aiqing, Kayne, Paul, Gargalovic, Peter, Kirchgessner, Todd, Pan, Calvin, Castellani, Lawrence W., Kostem, Emrah, Furlotte, Nicholas, Drake, Thomas A., Eskin, Eleazar, Lusis, Aldons J.
Publicado 2010

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

por Parks, Brian W., Nam, Elizabeth, Org, Elin, Kostem, Emrah, Norheim, Frode, Hui, Simon T., Pan, Calvin, Civelek, Mete, Rau, Christoph D., Bennett, Brian J., Mehrabian, Margarete, Ursell, Luke K., He, Aiqing, Castellani, Lawrence W., Zinker, Bradley, Kirby, Mark, Drake, Thomas A., Drevon, Christian A., Knight, Rob, Gargalovic, Peter, Kirchgessner, Todd, Eskin, Eleazar, Lusis, Aldons J.
Publicado 2013

Comparative Analysis of Proteome and Transcriptome Variation in Mouse

por Ghazalpour, Anatole, Bennett, Brian, Petyuk, Vladislav A., Orozco, Luz, Hagopian, Raffi, Mungrue, Imran N., Farber, Charles R., Sinsheimer, Janet, Kang, Hyun M., Furlotte, Nicholas, Park, Christopher C., Wen, Ping-Zi, Brewer, Heather, Weitz, Karl, Camp, David G., Pan, Calvin, Yordanova, Roumyana, Neuhaus, Isaac, Tilford, Charles, Siemers, Nathan, Gargalovic, Peter, Eskin, Eleazar, Kirchgessner, Todd, Smith, Desmond J., Smith, Richard D., Lusis, Aldons J.
Publicado 2011

11β-Hydroxysteroid Dehydrogenase Type 1 Gene Knockout Attenuates Atherosclerosis and In Vivo Foam Cell Formation in Hyperlipidemic apoE(−/−) Mice

por García, Ricardo A., Search, Debra J., Lupisella, John A., Ostrowski, Jacek, Guan, Bo, Chen, Jian, Yang, Wen-Pin, Truong, Amy, He, Aiqing, Zhang, Rongan, Yan, Mujing, Hellings, Samuel E., Gargalovic, Peter S., Ryan, Carol S., Watson, Linda M., Langish, Robert A., Shipkova, Petia A., Carson, Nancy L., Taylor, Joseph R., Yang, Richard, Psaltis, George C., Harrity, Thomas W., Robl, Jeffrey A., Gordon, David A.
Publicado 2013

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

por Civelek, Mete, Wu, Ying, Pan, Calvin, Raulerson, Chelsea K., Ko, Arthur, He, Aiqing, Tilford, Charles, Saleem, Niyas K., Stančáková, Alena, Scott, Laura J., Fuchsberger, Christian, Stringham, Heather M., Jackson, Anne U., Narisu, Narisu, Chines, Peter S., Small, Kerrin S., Kuusisto, Johanna, Parks, Brian W., Pajukanta, Päivi, Kirchgessner, Todd, Collins, Francis S., Gargalovic, Peter S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L., Lusis, Aldons J.
Publicado en Am J Hum Genet (2017)

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits

por Ghazalpour, Anatole, Rau, Christoph D., Farber, Charles R., Bennett, Brian J., Orozco, Luz D., van Nas, Atila, Pan, Calvin, Allayee, Hooman, Beaven, Simon W., Civelek, Mete, Davis, Richard C., Drake, Thomas A., Friedman, Rick A., Furlotte, Nick, Hui, Simon T., Jentsch, J. David, Kostem, Emrah, Kang, Hyun Min, Kang, Eun Yong, Joo, Jong Wha, Korshunov, Vyacheslav A., Laughlin, Rick E., Martin, Lisa J., Ohmen, Jeffrey D., Parks, Brian W., Pellegrini, Matteo, Reue, Karen, Smith, Desmond J., Tetradis, Sotirios, Wang, Jessica, Wang, Yibin, Weiss, James N., Kirchgessner, Todd, Gargalovic, Peter S., Eskin, Eleazar, Lusis, Aldons J., LeBoeuf, Renée C.
Publicado 2012