Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages

Many common diseases have an important inflammatory component mediated in part by macrophages. Here we used a systems genetics strategy to examine the role of common genetic variation in macrophage responses to inflammatory stimuli. We examined genome-wide transcript levels in macrophages from 92 st...

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Autors principals: Orozco, Luz D., Bennett, Brian J., Farber, Charles R., Ghazalpour, Anatole, Pan, Calvin, Che, Nam, Wen, Pingzi, Qi, Hong Xiu, Mutukulu, Adonisa, Siemers, Nathan, Neuhaus, Isaac, Yordanova, Roumyana, Gargalovic, Peter, Pellegrini, Matteo, Kirchgessner, Todd, Lusis, Aldons J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513387/
https://ncbi.nlm.nih.gov/pubmed/23101632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.043
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