Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages

Many common diseases have an important inflammatory component mediated in part by macrophages. Here we used a systems genetics strategy to examine the role of common genetic variation in macrophage responses to inflammatory stimuli. We examined genome-wide transcript levels in macrophages from 92 st...

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Detalhes bibliográficos
Main Authors: Orozco, Luz D., Bennett, Brian J., Farber, Charles R., Ghazalpour, Anatole, Pan, Calvin, Che, Nam, Wen, Pingzi, Qi, Hong Xiu, Mutukulu, Adonisa, Siemers, Nathan, Neuhaus, Isaac, Yordanova, Roumyana, Gargalovic, Peter, Pellegrini, Matteo, Kirchgessner, Todd, Lusis, Aldons J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513387/
https://ncbi.nlm.nih.gov/pubmed/23101632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.043
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