EGFR: Tale of the C-terminal tail

di Gajiwala, Ketan S
Pubblicazione 2013

Ack1: Activation and Regulation by Allostery

di Gajiwala, Ketan S., Maegley, Karen, Ferre, RoseAnn, He, You-Ai, Yu, Xiu
Pubblicazione 2013

Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes

di Zhao, Qian, Ouyang, Xiaohu, Wan, Xiaobo, Gajiwala, Ketan S., Kath, John C., Jones, Lyn H., Burlingame, Alma L., Taunton, Jack
Pubblicato in J Am Chem Soc (2017)

The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase

di Gajiwala, Ketan S., Grodsky, Neil, Bolaños, Ben, Feng, Junli, Ferre, RoseAnn, Timofeevski, Sergei, Xu, Meirong, Murray, Brion W., Johnson, Ted W., Stewart, Al
Pubblicato in J Biol Chem (2017)

Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers

di Qiu, Luping, Levine, Kymberly, Gajiwala, Ketan S., Cronin, Ciarán N., Nagata, Asako, Johnson, Eric, Kraus, Michelle, Tatlock, John, Kania, Robert, Foley, Timothy, Sun, Shaoxian
Pubblicato in PLoS One (2018)

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

di Zhang, Hui-Min, Yu, Xiu, Greig, Michael J, Gajiwala, Ketan S, Wu, Joe C, Diehl, Wade, Lunney, Elizabeth A, Emmett, Mark R, Marshall, Alan G
Pubblicazione 2010

Contribution of Hydrophobic Interactions to Protein Stability

di Pace, C. Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R., Shirley, Bret A., Hendricks, Marsha McNutt, Iimura, Satoshi, Gajiwala, Ketan, Scholtz, J. Martin, Grimsley, Gerald R.
Pubblicazione 2011

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

di Long, Yicheng, Bolanos, Ben, Gong, Lihu, Liu, Wei, Goodrich, Karen J, Yang, Xin, Chen, Siming, Gooding, Anne R, Maegley, Karen A, Gajiwala, Ketan S, Brooun, Alexei, Cech, Thomas R, Liu, Xin
Pubblicato in eLife (2017)

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance

di Brooun, Alexei, Gajiwala, Ketan S., Deng, Ya-Li, Liu, Wei, Bolaños, Ben, Bingham, Patrick, He, You-Ai, Diehl, Wade, Grable, Nicole, Kung, Pei-Pei, Sutton, Scott, Maegley, Karen A., Yu, Xiu, Stewart, Al E.
Pubblicato in Nat Commun (2016)

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

di Ryan, Kevin, Bolaňos, Ben, Smith, Marissa, Palde, Prakash B., Cuenca, Paulina Delgado, VanArsdale, Todd L., Niessen, Sherry, Zhang, Lianglin, Behenna, Douglas, Ornelas, Martha A., Tran, Khanh T., Kaiser, Stephen, Lum, Lawrence, Stewart, Al, Gajiwala, Ketan S.
Pubblicato in J Biol Chem (2021)

Proteome-wide map of targets of T790M-EGFR-directed covalent inhibitors

di Niessen, Sherry, Dix, Melissa M., Barbas, Sabrina, Potter, Zachary E., Lu, Shuyan, Brodsky, Oleg, Planken, Simon, Behenna, Douglas, Almaden, Chau, Gajiwala, Ketan S., Ryan, Kevin, Ferre, RoseAnn, Lazear, Michael R, Hayward, Matthew M., Kath, John C., Cravatt, Benjamin F.
Pubblicato in Cell Chem Biol (2017)

Contribution of hydrogen bonds to protein stability

di Pace, C Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R, Schell, David, Thurlkill, Richard L, Imura, Satoshi, Scholtz, J Martin, Gajiwala, Ketan, Sevcik, Jozef, Urbanikova, Lubica, Myers, Jeffery K, Takano, Kazufumi, Hebert, Eric J, Shirley, Bret A, Grimsley, Gerald R
Pubblicazione 2014

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

di Gajiwala, Ketan S., Wu, Joe C., Christensen, James, Deshmukh, Gayatri D., Diehl, Wade, DiNitto, Jonathan P., English, Jessie M., Greig, Michael J., He, You-Ai, Jacques, Suzanne L., Lunney, Elizabeth A., McTigue, Michele, Molina, David, Quenzer, Terri, Wells, Peter A., Yu, Xiu, Zhang, Yan, Zou, Aihua, Emmett, Mark R., Marshall, Alan G., Zhang, Hui-Min, Demetri, George D.
Pubblicazione 2009