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Contribution of hydrogen bonds to protein stability
Our goal was to gain a better understanding of the contribution of the burial of polar groups and their hydrogen bonds to the conformational stability of proteins. We measured the change in stability, Δ(ΔG), for a series of hydrogen bonding mutants in four proteins: villin headpiece subdomain (VHP)...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Wiley-Blackwell
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005716/ https://ncbi.nlm.nih.gov/pubmed/24591301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2449 |
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