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Urea denatured state ensembles contain extensive secondary structure that is increased in hydrophobic proteins
The goal of this article is to gain a better understanding of the denatured state ensemble (DSE) of proteins through an experimental and computational study of their denaturation by urea. Proteins unfold to different extents in urea and the most hydrophobic proteins have the most compact DSE and con...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868236/ https://ncbi.nlm.nih.gov/pubmed/20198681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.370 |
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