EGFR: Tale of the C-terminal tail

Tekijä Gajiwala, Ketan S
Julkaistu 2013

Ack1: Activation and Regulation by Allostery

Tekijä Gajiwala, Ketan S., Maegley, Karen, Ferre, RoseAnn, He, You-Ai, Yu, Xiu
Julkaistu 2013

Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes

Tekijä Zhao, Qian, Ouyang, Xiaohu, Wan, Xiaobo, Gajiwala, Ketan S., Kath, John C., Jones, Lyn H., Burlingame, Alma L., Taunton, Jack
Julkaisussa J Am Chem Soc (2017)

The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase

Tekijä Gajiwala, Ketan S., Grodsky, Neil, Bolaños, Ben, Feng, Junli, Ferre, RoseAnn, Timofeevski, Sergei, Xu, Meirong, Murray, Brion W., Johnson, Ted W., Stewart, Al
Julkaisussa J Biol Chem (2017)

Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers

Tekijä Qiu, Luping, Levine, Kymberly, Gajiwala, Ketan S., Cronin, Ciarán N., Nagata, Asako, Johnson, Eric, Kraus, Michelle, Tatlock, John, Kania, Robert, Foley, Timothy, Sun, Shaoxian
Julkaisussa PLoS One (2018)

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

Tekijä Zhang, Hui-Min, Yu, Xiu, Greig, Michael J, Gajiwala, Ketan S, Wu, Joe C, Diehl, Wade, Lunney, Elizabeth A, Emmett, Mark R, Marshall, Alan G
Julkaistu 2010

Contribution of Hydrophobic Interactions to Protein Stability

Tekijä Pace, C. Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R., Shirley, Bret A., Hendricks, Marsha McNutt, Iimura, Satoshi, Gajiwala, Ketan, Scholtz, J. Martin, Grimsley, Gerald R.
Julkaistu 2011

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

Tekijä Long, Yicheng, Bolanos, Ben, Gong, Lihu, Liu, Wei, Goodrich, Karen J, Yang, Xin, Chen, Siming, Gooding, Anne R, Maegley, Karen A, Gajiwala, Ketan S, Brooun, Alexei, Cech, Thomas R, Liu, Xin
Julkaisussa eLife (2017)

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance

Tekijä Brooun, Alexei, Gajiwala, Ketan S., Deng, Ya-Li, Liu, Wei, Bolaños, Ben, Bingham, Patrick, He, You-Ai, Diehl, Wade, Grable, Nicole, Kung, Pei-Pei, Sutton, Scott, Maegley, Karen A., Yu, Xiu, Stewart, Al E.
Julkaisussa Nat Commun (2016)

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

Tekijä Ryan, Kevin, Bolaňos, Ben, Smith, Marissa, Palde, Prakash B., Cuenca, Paulina Delgado, VanArsdale, Todd L., Niessen, Sherry, Zhang, Lianglin, Behenna, Douglas, Ornelas, Martha A., Tran, Khanh T., Kaiser, Stephen, Lum, Lawrence, Stewart, Al, Gajiwala, Ketan S.
Julkaisussa J Biol Chem (2021)

Proteome-wide map of targets of T790M-EGFR-directed covalent inhibitors

Tekijä Niessen, Sherry, Dix, Melissa M., Barbas, Sabrina, Potter, Zachary E., Lu, Shuyan, Brodsky, Oleg, Planken, Simon, Behenna, Douglas, Almaden, Chau, Gajiwala, Ketan S., Ryan, Kevin, Ferre, RoseAnn, Lazear, Michael R, Hayward, Matthew M., Kath, John C., Cravatt, Benjamin F.
Julkaisussa Cell Chem Biol (2017)

Contribution of hydrogen bonds to protein stability

Tekijä Pace, C Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R, Schell, David, Thurlkill, Richard L, Imura, Satoshi, Scholtz, J Martin, Gajiwala, Ketan, Sevcik, Jozef, Urbanikova, Lubica, Myers, Jeffery K, Takano, Kazufumi, Hebert, Eric J, Shirley, Bret A, Grimsley, Gerald R
Julkaistu 2014

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Tekijä Gajiwala, Ketan S., Wu, Joe C., Christensen, James, Deshmukh, Gayatri D., Diehl, Wade, DiNitto, Jonathan P., English, Jessie M., Greig, Michael J., He, You-Ai, Jacques, Suzanne L., Lunney, Elizabeth A., McTigue, Michele, Molina, David, Quenzer, Terri, Wells, Peter A., Yu, Xiu, Zhang, Yan, Zou, Aihua, Emmett, Mark R., Marshall, Alan G., Zhang, Hui-Min, Demetri, George D.
Julkaistu 2009