EGFR: Tale of the C-terminal tail

por Gajiwala, Ketan S
Publicado 2013

Ack1: Activation and Regulation by Allostery

por Gajiwala, Ketan S., Maegley, Karen, Ferre, RoseAnn, He, You-Ai, Yu, Xiu
Publicado 2013

Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes

por Zhao, Qian, Ouyang, Xiaohu, Wan, Xiaobo, Gajiwala, Ketan S., Kath, John C., Jones, Lyn H., Burlingame, Alma L., Taunton, Jack
Publicado en J Am Chem Soc (2017)

The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase

por Gajiwala, Ketan S., Grodsky, Neil, Bolaños, Ben, Feng, Junli, Ferre, RoseAnn, Timofeevski, Sergei, Xu, Meirong, Murray, Brion W., Johnson, Ted W., Stewart, Al
Publicado en J Biol Chem (2017)

Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers

por Qiu, Luping, Levine, Kymberly, Gajiwala, Ketan S., Cronin, Ciarán N., Nagata, Asako, Johnson, Eric, Kraus, Michelle, Tatlock, John, Kania, Robert, Foley, Timothy, Sun, Shaoxian
Publicado en PLoS One (2018)

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

por Zhang, Hui-Min, Yu, Xiu, Greig, Michael J, Gajiwala, Ketan S, Wu, Joe C, Diehl, Wade, Lunney, Elizabeth A, Emmett, Mark R, Marshall, Alan G
Publicado 2010

Contribution of Hydrophobic Interactions to Protein Stability

por Pace, C. Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R., Shirley, Bret A., Hendricks, Marsha McNutt, Iimura, Satoshi, Gajiwala, Ketan, Scholtz, J. Martin, Grimsley, Gerald R.
Publicado 2011

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

por Long, Yicheng, Bolanos, Ben, Gong, Lihu, Liu, Wei, Goodrich, Karen J, Yang, Xin, Chen, Siming, Gooding, Anne R, Maegley, Karen A, Gajiwala, Ketan S, Brooun, Alexei, Cech, Thomas R, Liu, Xin
Publicado en eLife (2017)

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance

por Brooun, Alexei, Gajiwala, Ketan S., Deng, Ya-Li, Liu, Wei, Bolaños, Ben, Bingham, Patrick, He, You-Ai, Diehl, Wade, Grable, Nicole, Kung, Pei-Pei, Sutton, Scott, Maegley, Karen A., Yu, Xiu, Stewart, Al E.
Publicado en Nat Commun (2016)

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

por Ryan, Kevin, Bolaňos, Ben, Smith, Marissa, Palde, Prakash B., Cuenca, Paulina Delgado, VanArsdale, Todd L., Niessen, Sherry, Zhang, Lianglin, Behenna, Douglas, Ornelas, Martha A., Tran, Khanh T., Kaiser, Stephen, Lum, Lawrence, Stewart, Al, Gajiwala, Ketan S.
Publicado en J Biol Chem (2021)

Proteome-wide map of targets of T790M-EGFR-directed covalent inhibitors

por Niessen, Sherry, Dix, Melissa M., Barbas, Sabrina, Potter, Zachary E., Lu, Shuyan, Brodsky, Oleg, Planken, Simon, Behenna, Douglas, Almaden, Chau, Gajiwala, Ketan S., Ryan, Kevin, Ferre, RoseAnn, Lazear, Michael R, Hayward, Matthew M., Kath, John C., Cravatt, Benjamin F.
Publicado en Cell Chem Biol (2017)

Contribution of hydrogen bonds to protein stability

por Pace, C Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R, Schell, David, Thurlkill, Richard L, Imura, Satoshi, Scholtz, J Martin, Gajiwala, Ketan, Sevcik, Jozef, Urbanikova, Lubica, Myers, Jeffery K, Takano, Kazufumi, Hebert, Eric J, Shirley, Bret A, Grimsley, Gerald R
Publicado 2014

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

por Gajiwala, Ketan S., Wu, Joe C., Christensen, James, Deshmukh, Gayatri D., Diehl, Wade, DiNitto, Jonathan P., English, Jessie M., Greig, Michael J., He, You-Ai, Jacques, Suzanne L., Lunney, Elizabeth A., McTigue, Michele, Molina, David, Quenzer, Terri, Wells, Peter A., Yu, Xiu, Zhang, Yan, Zou, Aihua, Emmett, Mark R., Marshall, Alan G., Zhang, Hui-Min, Demetri, George D.
Publicado 2009