EGFR: Tale of the C-terminal tail

Autor Gajiwala, Ketan S
Vydáno 2013

Ack1: Activation and Regulation by Allostery

Autor Gajiwala, Ketan S., Maegley, Karen, Ferre, RoseAnn, He, You-Ai, Yu, Xiu
Vydáno 2013

Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes

Autor Zhao, Qian, Ouyang, Xiaohu, Wan, Xiaobo, Gajiwala, Ketan S., Kath, John C., Jones, Lyn H., Burlingame, Alma L., Taunton, Jack
Vydáno v J Am Chem Soc (2017)

The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase

Autor Gajiwala, Ketan S., Grodsky, Neil, Bolaños, Ben, Feng, Junli, Ferre, RoseAnn, Timofeevski, Sergei, Xu, Meirong, Murray, Brion W., Johnson, Ted W., Stewart, Al
Vydáno v J Biol Chem (2017)

Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers

Autor Qiu, Luping, Levine, Kymberly, Gajiwala, Ketan S., Cronin, Ciarán N., Nagata, Asako, Johnson, Eric, Kraus, Michelle, Tatlock, John, Kania, Robert, Foley, Timothy, Sun, Shaoxian
Vydáno v PLoS One (2018)

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

Autor Zhang, Hui-Min, Yu, Xiu, Greig, Michael J, Gajiwala, Ketan S, Wu, Joe C, Diehl, Wade, Lunney, Elizabeth A, Emmett, Mark R, Marshall, Alan G
Vydáno 2010

Contribution of Hydrophobic Interactions to Protein Stability

Autor Pace, C. Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R., Shirley, Bret A., Hendricks, Marsha McNutt, Iimura, Satoshi, Gajiwala, Ketan, Scholtz, J. Martin, Grimsley, Gerald R.
Vydáno 2011

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

Autor Long, Yicheng, Bolanos, Ben, Gong, Lihu, Liu, Wei, Goodrich, Karen J, Yang, Xin, Chen, Siming, Gooding, Anne R, Maegley, Karen A, Gajiwala, Ketan S, Brooun, Alexei, Cech, Thomas R, Liu, Xin
Vydáno v eLife (2017)

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance

Autor Brooun, Alexei, Gajiwala, Ketan S., Deng, Ya-Li, Liu, Wei, Bolaños, Ben, Bingham, Patrick, He, You-Ai, Diehl, Wade, Grable, Nicole, Kung, Pei-Pei, Sutton, Scott, Maegley, Karen A., Yu, Xiu, Stewart, Al E.
Vydáno v Nat Commun (2016)

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

Autor Ryan, Kevin, Bolaňos, Ben, Smith, Marissa, Palde, Prakash B., Cuenca, Paulina Delgado, VanArsdale, Todd L., Niessen, Sherry, Zhang, Lianglin, Behenna, Douglas, Ornelas, Martha A., Tran, Khanh T., Kaiser, Stephen, Lum, Lawrence, Stewart, Al, Gajiwala, Ketan S.
Vydáno v J Biol Chem (2021)

Proteome-wide map of targets of T790M-EGFR-directed covalent inhibitors

Autor Niessen, Sherry, Dix, Melissa M., Barbas, Sabrina, Potter, Zachary E., Lu, Shuyan, Brodsky, Oleg, Planken, Simon, Behenna, Douglas, Almaden, Chau, Gajiwala, Ketan S., Ryan, Kevin, Ferre, RoseAnn, Lazear, Michael R, Hayward, Matthew M., Kath, John C., Cravatt, Benjamin F.
Vydáno v Cell Chem Biol (2017)

Contribution of hydrogen bonds to protein stability

Autor Pace, C Nick, Fu, Hailong, Fryar, Katrina Lee, Landua, John, Trevino, Saul R, Schell, David, Thurlkill, Richard L, Imura, Satoshi, Scholtz, J Martin, Gajiwala, Ketan, Sevcik, Jozef, Urbanikova, Lubica, Myers, Jeffery K, Takano, Kazufumi, Hebert, Eric J, Shirley, Bret A, Grimsley, Gerald R
Vydáno 2014

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Autor Gajiwala, Ketan S., Wu, Joe C., Christensen, James, Deshmukh, Gayatri D., Diehl, Wade, DiNitto, Jonathan P., English, Jessie M., Greig, Michael J., He, You-Ai, Jacques, Suzanne L., Lunney, Elizabeth A., McTigue, Michele, Molina, David, Quenzer, Terri, Wells, Peter A., Yu, Xiu, Zhang, Yan, Zou, Aihua, Emmett, Mark R., Marshall, Alan G., Zhang, Hui-Min, Demetri, George D.
Vydáno 2009