Physiologically based pharmacokinetic model of lapatinib developed in mice and scaled to humans

Por Hudachek, Susan F., Gustafson, Daniel L.
Publicado em 2013

Incorporation of ABCB1-mediated transport into a physiologically-based pharmacokinetic model of docetaxel in mice

Por Hudachek, Susan F., Gustafson, Daniel L.
Publicado no J Pharmacokinet Pharmacodyn (2013)

Pharmacokinetics and pharmacodynamics of AZD6244 (ARRY-142886) in tumor-bearing nude mice

Por Denton, Cathrine L., Gustafson, Daniel L.
Publicado no Cancer Chemother Pharmacol (2010)

Coadministration of lapatinib increases exposure to docetaxel but not doxorubicin in the small intestine of mice

Por Hudachek, Susan F., Gustafson, Daniel L.
Publicado no Anticancer Drugs (2013)

Autophagy and Cancer Therapy

Por Thorburn, Andrew, Thamm, Douglas H., Gustafson, Daniel L.
Publicado em 2014

Phase I Pharmacokinetic and Pharmacodynamic Evaluation of Combined Valproic Acid/Doxorubicin Treatment in Dogs with Spontaneous Cancer

Por Wittenburg, Luke A., Gustafson, Daniel L., Thamm, Douglas H.
Publicado em 2010

Rapid and sensitive LC–MS/MS method for determination of felbamate in mouse plasma and tissues and human plasma

Por Hansen, Ryan J., Samber, Bradley J., Gustafson, Daniel L.
Publicado no J Chromatogr B Analyt Technol Biomed Life Sci (2010)

Hydroxychloroquine: A Physiologically-Based Pharmacokinetic Model in the Context of Cancer-Related Autophagy Modulation

Por Collins, Keagan P., Jackson, Kristen M., Gustafson, Daniel L.
Publicado no J Pharmacol Exp Ther (2018)

Drug Selection in the Genomic Age: Application of the Coexpression Extrapolation Principle for Drug Repositioning in Cancer Therapy

Por Gustafson, Daniel L., Fowles, Jared S., Brown, Kristen C., Theodorescu, Dan
Publicado no Assay Drug Dev Technol (2015)

Doxorubicin area under the curve is an important predictor of neutropenia in dogs with naturally occurring cancers

Por Wittenburg, Luke A., Weishaar, Kristen, Ramirez, Dominique, Gustafson, Daniel L.
Publicado no Vet Comp Oncol (2019)

Simultaneous absolute quantitation of ATP-binding cassette transporters in normal dog tissues by signature peptide analysis using a LC/MS/MS method

Por Wittenburg, Luke A., Ramirez, Dominique, Conger, Holly, Gustafson, Daniel L.
Publicado no Res Vet Sci (2018)

A systematic analysis of genomics-based modeling approaches for prediction of drug response to cytotoxic chemotherapies

Por Mannheimer, Joshua D., Duval, Dawn L., Prasad, Ashok, Gustafson, Daniel L.
Publicado no BMC Med Genomics (2019)

Pharmacokinetic-Directed Dosing of Vandetanib and Docetaxel in a Mouse Model of Human Squamous Cell Carcinoma

Por Bradshaw-Pierce, Erica L., Steinhauer, Courtney A., Raben, David, Gustafson, Daniel L.
Publicado em 2008

Canine sarcomas as a surrogate for the human disease

Por Gustafson, Daniel L., Duval, Dawn L., Regan, Daniel P., Thamm, Douglas H.
Publicado no Pharmacol Ther (2018)

Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing

Por Das, Sunetra, Idate, Rupa, Cronise, Kathryn E., Gustafson, Daniel L., Duval, Dawn L.
Publicado no Mol Cancer Ther (2019)

Expression of Human NAD(P)H:Quinone Oxidoreductase (DT-Diaphorase) in Chinese Hamster Ovary Cells: Effect on the Toxicity of Antitumor Quinones

Por GUSTAFSON, DANIEL L., BEALL, HOWARD D., BOLTON, EMIKO M., ROSS, DAVID, WALDREN, CHARLES A.
Publicado em 1996

Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma

Por Fowles, Jared S., Brown, Kristen C., Hess, Ann M., Duval, Dawn L., Gustafson, Daniel L.
Publicado no BMC Bioinformatics (2016)

Docetaxel Accumulates in Lymphatic Circulation Following Subcutaneous Delivery as Compared to Intravenous Delivery in Rats

Por WORLEY, DEANNA R., HANSEN, RYAN J., WITTENBURG, LUKE A., CHUBB, LAURA S., GUSTAFSON, DANIEL L.
Publicado no Anticancer Res (2016)

Optimized dosing of a CCR2 antagonist for amplification of vaccine immunity

Por Mitchell, Leah A., Hansen, Ryan J., Beaupre, Adam J., Gustafson, Daniel L., Dow, Steven W.
Publicado em 2012

Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics

Por Ramirez, Dominique A., Collins, Keagan P., Aradi, Allister E., Conger, Katherine A., Gustafson, Daniel L.
Publicado no Drug Metab Dispos (2019)