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Optimized dosing of a CCR2 antagonist for amplification of vaccine immunity
We have recently discovered that inflammatory monocytes recruited to lymph nodes in response to vaccine-induced inflammation can function as potent negative regulators of both humoral and cell-mediated immune responses to vaccination. Monocyte depletion or migration blockade can significantly amplif...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875337/ https://ncbi.nlm.nih.gov/pubmed/23246255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2012.11.016 |
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