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Expression of Human NAD(P)H:Quinone Oxidoreductase (DT-Diaphorase) in Chinese Hamster Ovary Cells: Effect on the Toxicity of Antitumor Quinones

Previous studies have indicated that NAD(P)H:quinone oxidoreductase [DT-diaphorase (NQO1)] plays an important role in the bioreductive activation of quinone-containing antitumor agents. Although these studies demonstrated that purified NQO1 can reduce these compounds in vitro, the importance NQO1 in...

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Detalhes bibliográficos
Main Authors: GUSTAFSON, DANIEL L., BEALL, HOWARD D., BOLTON, EMIKO M., ROSS, DAVID, WALDREN, CHARLES A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883621/
https://ncbi.nlm.nih.gov/pubmed/8863816
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