Cationic amphiphilic drugs cause a marked expansion of apparent lysosomal volume: Implications for an intracellular distribution-based drug interaction

od Funk, Ryan S., Krise, Jeffrey P.
Izdano 2012

Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources

od Becker, Mara L., Funk, Ryan S.
izdano v Clin Transl Sci (2017)

3019 Metabolomic Markers of Methotrexate Response in Juvenile Idiopathic Arthritis

od Funk, Ryan Sol, Becker, Mara
izdano v J Clin Transl Sci (2019)

Defining a therapeutic window for rituximab maintenance therapy in ANCA-associated vasculitis

od Springer, Jason Michael, Funk, Ryan
izdano v J Clin Rheumatol (2021)

Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro

od Funk, Ryan S., Singh, Rakesh K., Becker, Mara L.
izdano v Clin Transl Sci (2019)

Mechanisms of amine accumulation in, and egress from, lysosomes

od Goldman, Stephen DB, Funk, Ryan S, Rajewski, Roger A, Krise, Jeffrey P
Izdano 2009

Low-Dose Methotrexate Results in the Selective Accumulation of Aminoimidazole Carboxamide Ribotide in an Erythroblastoid Cell Line

od Funk, Ryan S., van Haandel, Leon, Becker, Mara L., Leeder, J. Steven
Izdano 2013

Folate Depletion and Increased Glutamation in Juvenile Idiopathic Arthritis Patients Treated with Methotrexate

od Funk, Ryan S., van Haandel, Leon, Leeder, J. Steven, Becker, Mara L.
izdano v Arthritis Rheumatol (2014)

Altered Folate Homeostasis in Children with Down syndrome: A Potential Basis for Enhanced Methotrexate Toxicity

od Funk, Ryan S., Talib, Nasreen, Zimmerman, Kanecia, van Haandel, Leon, Becker, Mara L.
izdano v J Pediatr (2020)

Facing Real-World Challenges of Immunogenicity in Pediatric Inflammatory Bowel Disease

od Gress, Kyle, Bass, Julie A., Funk, Ryan S., Morrow, Ryan P., Hasenkamp, Rachel, Shakhnovich, Valentina
izdano v Front Immunol (2020)

Lysosomal Sequestration (Trapping) of Lipophilic Amine (Cationic Amphiphilic) Drugs in Immortalized Human Hepatocytes (Fa2N-4 Cells)

od Kazmi, Faraz, Hensley, Tiffini, Pope, Chad, Funk, Ryan S., Loewen, Greg J., Buckley, David B., Parkinson, Andrew
Izdano 2013

Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model

od Singh, Rakesh K., van Haandel, Leon, Kiptoo, Paul, Becker, Mara L., Siahaan, Teruna J., Funk, Ryan S.
izdano v Eur J Pharmacol (2019)

Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study

od Funk, Ryan S., Shakhnovich, Valentina, Cho, Yu Kyoung, Polireddy, Kishore, Jausurawong, Taina, Gress, Kyle, Becker, Mara L.
izdano v Pediatr Rheumatol Online J (2021)

Potential Role of Methotrexate Polyglutamates in Therapeutic Drug Monitoring for Pediatric Inflammatory Bowel Disease

od Morrow, Ryan, Funk, Ryan, Becker, Mara, Sherman, Ashley, Van Haandel, Leon, Hudson, Taina, Casini, Rebecca, Shakhnovich, Valentina
izdano v Pharmaceuticals (Basel) (2021)

Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 In Vivo

od Springer, Jason M., Raveendran, Vineesh V., Zhang, Mingcai, Funk, Ryan, Smith, Donald D., Maz, Mehrdad, Dileepan, Kottarappat N.
izdano v Mediators Inflamm (2019)

Variability in Potency Among Commercial Preparations of Berberine

od Funk, Ryan S., Singh, Rakesh K., Winefield, Robert D., Kandel, Sylvie E., Ruisinger, Janelle F., Moriarty, Patrick M., Backes, James M.
izdano v J Diet Suppl (2017)

Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP

od Singh, Rakesh K., van Haandel, Leon, Heruth, Daniel P., Ye, Shui Q., Leeder, J. Steven, Becker, Mara L., Funk, Ryan S.
izdano v J Pharmacol Exp Ther (2018)

Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic mice

od Funk, Ryan K., Maxwell, Taylor J., Izumi, Masayo, Edwin, Deepa, Kreisel, Friederike, Ley, Timothy J., Cheverud, James M., Graubert, Timothy A.
Izdano 2008

Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker‐driven precision dosing

od Oni‐Orisan, Akinyemi, Srinivas, Nithya, Mehta, Krina, Das, Jesmin Lohy, Nguyen, Thu T., Tison, Geoffrey H., Bauer, Scott R., Burian, Maria, Funk, Ryan S., Graham, Richard A.
izdano v Clin Transl Sci (2021)

Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: a case report

od Funk, Ryan K, Ferraro, Daniel J, Perrin, Richard J, Hurth, Kyle M, Stephens, John J, Mansur, David B, Chicoine, Michael R, Simpson, Joseph R, Jaboin, Jerry J
Izdano 2012