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Folate Depletion and Increased Glutamation in Juvenile Idiopathic Arthritis Patients Treated with Methotrexate

OBJECTIVE: Folates exist as a fluctuating pool of polyglutamated metabolites that may serve as a clinical marker of MTX activity. This study evaluates circulating folate content and folate polyglutamate distribution in Juvenile Idiopathic Arthritis (JIA) patients and in a cell culture model based on...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Funk, Ryan S., van Haandel, Leon, Leeder, J. Steven, Becker, Mara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376251/
https://ncbi.nlm.nih.gov/pubmed/25186097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38865
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