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Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model
Methotrexate (MTX) efficacy in autoimmune arthritis is variable and unpredictable resulting in the need for the identification of biomarkers to guide drug therapy. This study utilizes the collagen-induced arthritis mouse model to investigate erythrocyte MTX disposition and anti-folate activity as bi...
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| Publicado no: | Eur J Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6500488/ https://ncbi.nlm.nih.gov/pubmed/30951714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2019.03.052 |
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