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Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model

Methotrexate (MTX) efficacy in autoimmune arthritis is variable and unpredictable resulting in the need for the identification of biomarkers to guide drug therapy. This study utilizes the collagen-induced arthritis mouse model to investigate erythrocyte MTX disposition and anti-folate activity as bi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Pharmacol
Egile Nagusiak: Singh, Rakesh K., van Haandel, Leon, Kiptoo, Paul, Becker, Mara L., Siahaan, Teruna J., Funk, Ryan S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500488/
https://ncbi.nlm.nih.gov/pubmed/30951714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2019.03.052
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