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Altered Folate Homeostasis in Children with Down syndrome: A Potential Basis for Enhanced Methotrexate Toxicity
Methotrexate (MTX) is used to treat autoimmune and oncologic diseases in children with Down syndrome (DS). However, increased MTX-related toxicity is reported in this population. We evaluated differences in the concentrations and distribution of erythrocyte folates in children with DS as a potential...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Pediatr |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247922/ https://ncbi.nlm.nih.gov/pubmed/32111377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2020.01.032 |
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