Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic mice

Therapy-related acute myelogenous leukemia (t-AML) is an important late adverse effect of alkylator chemotherapy. Susceptibility to t-AML has a genetic component, yet specific genetic variants that influence susceptibility are poorly understood. We analyzed an F(2) intercross (n = 282 mice) between...

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Detalhes bibliográficos
Main Authors: Funk, Ryan K., Maxwell, Taylor J., Izumi, Masayo, Edwin, Deepa, Kreisel, Friederike, Ley, Timothy J., Cheverud, James M., Graubert, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515115/
https://ncbi.nlm.nih.gov/pubmed/18552208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-132084
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