Cationic amphiphilic drugs cause a marked expansion of apparent lysosomal volume: Implications for an intracellular distribution-based drug interaction

gan Funk, Ryan S., Krise, Jeffrey P.
Cyhoeddwyd 2012

Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources

gan Becker, Mara L., Funk, Ryan S.
Cyhoeddwyd yn Clin Transl Sci (2017)

3019 Metabolomic Markers of Methotrexate Response in Juvenile Idiopathic Arthritis

gan Funk, Ryan Sol, Becker, Mara
Cyhoeddwyd yn J Clin Transl Sci (2019)

Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro

gan Funk, Ryan S., Singh, Rakesh K., Becker, Mara L.
Cyhoeddwyd yn Clin Transl Sci (2019)

Mechanisms of amine accumulation in, and egress from, lysosomes

gan Goldman, Stephen DB, Funk, Ryan S, Rajewski, Roger A, Krise, Jeffrey P
Cyhoeddwyd 2009

Low-Dose Methotrexate Results in the Selective Accumulation of Aminoimidazole Carboxamide Ribotide in an Erythroblastoid Cell Line

gan Funk, Ryan S., van Haandel, Leon, Becker, Mara L., Leeder, J. Steven
Cyhoeddwyd 2013

Folate Depletion and Increased Glutamation in Juvenile Idiopathic Arthritis Patients Treated with Methotrexate

gan Funk, Ryan S., van Haandel, Leon, Leeder, J. Steven, Becker, Mara L.
Cyhoeddwyd yn Arthritis Rheumatol (2014)

Altered Folate Homeostasis in Children with Down syndrome: A Potential Basis for Enhanced Methotrexate Toxicity

gan Funk, Ryan S., Talib, Nasreen, Zimmerman, Kanecia, van Haandel, Leon, Becker, Mara L.
Cyhoeddwyd yn J Pediatr (2020)

Facing Real-World Challenges of Immunogenicity in Pediatric Inflammatory Bowel Disease

gan Gress, Kyle, Bass, Julie A., Funk, Ryan S., Morrow, Ryan P., Hasenkamp, Rachel, Shakhnovich, Valentina
Cyhoeddwyd yn Front Immunol (2020)

Lysosomal Sequestration (Trapping) of Lipophilic Amine (Cationic Amphiphilic) Drugs in Immortalized Human Hepatocytes (Fa2N-4 Cells)

gan Kazmi, Faraz, Hensley, Tiffini, Pope, Chad, Funk, Ryan S., Loewen, Greg J., Buckley, David B., Parkinson, Andrew
Cyhoeddwyd 2013

Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model

gan Singh, Rakesh K., van Haandel, Leon, Kiptoo, Paul, Becker, Mara L., Siahaan, Teruna J., Funk, Ryan S.
Cyhoeddwyd yn Eur J Pharmacol (2019)

Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 In Vivo

gan Springer, Jason M., Raveendran, Vineesh V., Zhang, Mingcai, Funk, Ryan, Smith, Donald D., Maz, Mehrdad, Dileepan, Kottarappat N.
Cyhoeddwyd yn Mediators Inflamm (2019)

Variability in Potency Among Commercial Preparations of Berberine

gan Funk, Ryan S., Singh, Rakesh K., Winefield, Robert D., Kandel, Sylvie E., Ruisinger, Janelle F., Moriarty, Patrick M., Backes, James M.
Cyhoeddwyd yn J Diet Suppl (2017)

Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP

gan Singh, Rakesh K., van Haandel, Leon, Heruth, Daniel P., Ye, Shui Q., Leeder, J. Steven, Becker, Mara L., Funk, Ryan S.
Cyhoeddwyd yn J Pharmacol Exp Ther (2018)

Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic mice

gan Funk, Ryan K., Maxwell, Taylor J., Izumi, Masayo, Edwin, Deepa, Kreisel, Friederike, Ley, Timothy J., Cheverud, James M., Graubert, Timothy A.
Cyhoeddwyd 2008

Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: a case report

gan Funk, Ryan K, Ferraro, Daniel J, Perrin, Richard J, Hurth, Kyle M, Stephens, John J, Mansur, David B, Chicoine, Michael R, Simpson, Joseph R, Jaboin, Jerry J
Cyhoeddwyd 2012

Immunogenicity in Clinical Practice and Drug Development: When is it Significant?

gan Shakhnovich, Valentina, Meibohm, Bernd, Rosenberg, Amy, Kierzek, Andrzej M., Hasenkamp, Rachel, Funk, Ryan S., Thalhauser, Craig J., van der Graaf, Piet H., Wang, Yow‐Ming C., Hamuro, Lora
Cyhoeddwyd yn Clin Transl Sci (2019)

Precision Pharmacotherapy: Integrating Pharmacogenomics into Clinical Pharmacy Practice

gan Hicks, J. Kevin, Aquilante, Christina L., Dunnenberger, Henry M., Gammal, Roseann S., Funk, Ryan S., Aitken, Samuel L., Bright, David R., Coons, James C., Dotson, Kierra M., Elder, Christopher T., Groff, Lindsey T., Lee, James C.
Cyhoeddwyd yn J Am Coll Clin Pharm (2019)

A retrospective analysis of survival and prognostic factors after stereotactic radiosurgery for aggressive meningiomas

gan Ferraro, Daniel J, Funk, Ryan K, Blackett, John William, Ju, Michelle R, DeWees, Todd A, Chicoine, Michael R, Dowling, Joshua L, Rich, Keith M, Drzymala, Robert E, Zoberi, Imran, Simpson, Joseph R, Jaboin, Jerry J
Cyhoeddwyd 2014

The Rare Cancer Network: Ongoing Studies and Future Strategy

gan Ozsahin, Mahmut, Mirimanoff, René-Olivier, Thariat, Juliette, Sun, Xu Shan, Atalar, Banu, Lassen-Ramshad, Yasmin, Ugurluer, Gamze, Krishnan, Sunil, Hallemeier, Christopher, Houtte, Paul Van, Krengli, Marco, Zhang, Lan Jun, Chang, Kenneth, Funk, Ryan, Rooney, Jessica, Miller, Robert C.
Cyhoeddwyd 2014