The RP-p53-Mdm2 pathway: A new link to genetic integrity?: Comment on: Llanos S, et al. Cell Cycle 2010; 9:4005–12.

Por Frum, Rebecca A, Zhang, Yanping
Publicado em 2010

Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells

Por Frum, Rebecca A., Khondker, Zakaria S., Kaufman, David G.
Publicado em 2009

Use of the DNA Fiber Spreading Technique to Detect the Effects of Mutant p53 on DNA Replication

Por Frum, Rebecca A., Deb, Sumitra, Deb, Swati Palit
Publicado no Methods Mol Biol (2013)

Temporal and Functional Analysis of DNA Replicated in Early S Phase

Por Kaufman, David G., Cohen, Stephanie M., Frum, Rebecca A., Chastain, Paul D.
Publicado em 2010

DNA replication in early S phase pauses near newly activated origins

Por Frum, Rebecca A., Chastain, Paul D., Qu, Pingping, Cohen, Stephanie M., Kaufman, David G.
Publicado em 2008

Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication

Por Singh, Shilpa, Vaughan, Catherine A., Frum, Rebecca A., Grossman, Steven R., Deb, Sumitra, Palit Deb, Swati
Publicado no J Clin Invest (2017)

HDM2-Binding Partners: Interaction with Translation Elongation Factor EF1α

Por Frum, Rebecca, Busby, Scott A., Ramamoorthy, Mahesh, Deb, Sumitra, Shabanowitz, Jeffrey, Hunt, Donald F., Deb, Swati P.
Publicado no J Proteome Res (2007)

Allele specific gain-of-function activity of p53 mutants in lung cancer cells

Por Vaughan, Catherine A, Frum, Rebecca, Pearsall, Isabella, Singh, Shilpa, Windle, Brad, Yeudall, Andrew, Deb, Swati P., Deb, Sumitra
Publicado no Biochem Biophys Res Commun (2012)

Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination

Por Frum, Rebecca A., Love, Ian M., Damle, Priyadarshan, Mukhopadhyay, Nitai D., Deb, Swati Palit, Deb, Sumitra, Grossman, Steven R.
Publicado no Mol Cancer Res (2016)

Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl

Por Vaughan, Catherine A., Singh, Shilpa, Windle, Brad, Yeudall, W. Andrew, Frum, Rebecca, Grossman, Steven R., Deb, Swati P., Deb, Sumitra
Publicado em 2012

The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing

Por Frum, Rebecca A., Singh, Shilpa, Vaughan, Catherine, Mukhopadhyay, Nitai D., Grossman, Steven R., Windle, Brad, Deb, Sumitra, Deb, Swati Palit
Publicado em 2014