Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it?

Por Freitas-Junior, Lucio H., Chatelain, Eric, Kim, Helena Andrade, Siqueira-Neto, Jair L.
Publicado em 2012

A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation

Por Figueiredo, Luisa M., Freitas-Junior, Lúcio H., Bottius, Emmanuel, Olivo-Marin, Jean-Christophe, Scherf, Artur
Publicado em 2002

An Image Analysis Algorithm for Malaria Parasite Stage Classification and Viability Quantification

Por Moon, Seunghyun, Lee, Sukjun, Kim, Heechang, Freitas-Junior, Lucio H., Kang, Myungjoo, Ayong, Lawrence, Hansen, Michael A. E.
Publicado em 2013

Quantum dots: a new tool for anti-malarial drug assays

Por Ku, Min-Je, Dossin, Fernando M, Choi, Youngseon, Moraes, Carolina B, Ryu, Jiyoung, Song, Rita, Freitas-Junior, Lucio H
Publicado em 2011

An Image-Based Drug Susceptibility Assay Targeting the Placental Sequestration of Plasmodium falciparum-Infected Erythrocytes

Por Ku, Min-Je, Dossin, Fernando de M., Hansen, Michael A. E., Genovesio, Auguste, Ayong, Lawrence, Freitas-Junior, Lucio H.
Publicado em 2012

An Image-Based Algorithm for Precise and Accurate High Throughput Assessment of Drug Activity against the Human Parasite Trypanosoma cruzi

Por Moon, Seunghyun, Siqueira-Neto, Jair L., Moraes, Carolina Borsoi, Yang, Gyongseon, Kang, Myungjoo, Freitas-Junior, Lucio H., Hansen, Michael A. E.
Publicado em 2014

Proteomic-Based Approach To Gain Insight into Reprogramming of THP-1 Cells Exposed to Leishmania donovani over an Early Temporal Window

Por Singh, Alok Kumar, Pandey, Rajeev Kumar, Siqueira-Neto, Jair Lage, Kwon, Yong-Jun, Freitas-Junior, Lucio H., Shaha, Chandrima, Madhubala, Rentala
Publicado no Infect Immun (2015)

Transcription Sites Are Developmentally Regulated during the Asexual Cycle of Plasmodium falciparum

Por Moraes, Carolina B., Dorval, Thierry, Contreras-Dominguez, Mónica, Dossin, Fernando de M., Hansen, Michael A. E., Genovesio, Auguste, Freitas-Junior, Lucio H.
Publicado em 2013

Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development

Por Moraes, Carolina B., Giardini, Miriam A., Kim, Hwayoung, Franco, Caio H., Araujo-Junior, Adalberto M., Schenkman, Sergio, Chatelain, Eric, Freitas-Junior, Lucio H.
Publicado em 2014

An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages

Por Siqueira-Neto, Jair L., Moon, Seunghyun, Jang, Jiyeon, Yang, Gyongseon, Lee, Changbok, Moon, Hong Kee, Chatelain, Eric, Genovesio, Auguste, Cechetto, Jonathan, Freitas-Junior, Lucio H.
Publicado em 2012

A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes

Por O’Donnell, Rebecca A., Freitas-Junior, Lúcio H., Preiser, Peter R., Williamson, Donald H., Duraisingh, Manoj, McElwain, Terry F., Scherf, Artur, Cowman, Alan F., Crabb, Brendan S.
Publicado em 2002

Automated Nuclear Analysis of Leishmania major Telomeric Clusters Reveals Changes in Their Organization during the Parasite's Life Cycle

Por Dossin, Fernando de M., Dufour, Alexandre, Dusch, Elodie, Siqueira-Neto, Jair L., Moraes, Carolina B., Yang, Gyong Seon, Cano, Maria Isabel, Genovesio, Auguste, Freitas-Junior, Lucio H.
Publicado em 2008

Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity

Por No, Joo Hwan, de Macedo Dossin, Fernando, Zhang, Yonghui, Liu, Yi-Liang, Zhu, Wei, Feng, Xinxin, Yoo, Jinyoung Anny, Lee, Eunhae, Wang, Ke, Hui, Raymond, Freitas-Junior, Lucio H., Oldfield, Eric
Publicado em 2012

Identification of Novel Compounds Inhibiting Chikungunya Virus-Induced Cell Death by High Throughput Screening of a Kinase Inhibitor Library

Por Cruz, Deu John M., Bonotto, Rafaela M., Gomes, Rafael G. B., da Silva, Camila T., Taniguchi, Juliana B., No, Joo Hwan, Lombardot, Benoit, Schwartz, Olivier, Hansen, Michael A. E., Freitas-Junior, Lucio H.
Publicado em 2013

Antileishmanial High-Throughput Drug Screening Reveals Drug Candidates with New Scaffolds

Por Siqueira-Neto, Jair L., Song, Ok-Ryul, Oh, Hyunrim, Sohn, Jeong-Hun, Yang, Gyongseon, Nam, Jiyoun, Jang, Jiyeon, Cechetto, Jonathan, Lee, Chang Bok, Moon, Seunghyun, Genovesio, Auguste, Chatelain, Eric, Christophe, Thierry, Freitas-Junior, Lucio H.
Publicado em 2010

Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection

Por Genovesio, Auguste, Giardini, Miriam A., Kwon, Yong-Jun, Dossin, Fernando de Macedo, Choi, Seo Yeon, Kim, Nam Youl, Kim, Hi Chul, Jung, Sung Yong, Schenkman, Sergio, Almeida, Igor C., Emans, Neil, Freitas-Junior, Lucio H.
Publicado em 2011

An Essential Nuclear Protein in Trypanosomes Is a Component of mRNA Transcription/Export Pathway

Por Serpeloni, Mariana, Moraes, Carolina Borsoi, Muniz, João Renato Carvalho, Motta, Maria Cristina Machado, Ramos, Augusto Savio Peixoto, Kessler, Rafael Luis, Inoue, Alexandre Haruo, Duarte daRocha, Wanderson, Yamada-Ogatta, Sueli Fumie, Fragoso, Stenio Perdigão, Goldenberg, Samuel, Freitas-Junior, Lucio H., Ávila, Andréa Rodrigues
Publicado em 2011