An Image-Based Algorithm for Precise and Accurate High Throughput Assessment of Drug Activity against the Human Parasite Trypanosoma cruzi

We present a customized high content (image-based) and high throughput screening algorithm for the quantification of Trypanosoma cruzi infection in host cells. Based solely on DNA staining and single-channel images, the algorithm precisely segments and identifies the nuclei and cytoplasm of mammalia...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Moon, Seunghyun, Siqueira-Neto, Jair L., Moraes, Carolina Borsoi, Yang, Gyongseon, Kang, Myungjoo, Freitas-Junior, Lucio H., Hansen, Michael A. E.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913590/
https://ncbi.nlm.nih.gov/pubmed/24503652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087188
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы