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High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi

Chagas disease, caused by the kinetoplastid parasite Trypanosoma cruzi, affects between 6 and 7 million people worldwide, with an estimated 300,000 to 1 million of these cases in the United States. In the chronic phase of infection, T. cruzi can cause severe gastrointestinal and cardiac disease, whi...

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Dettagli Bibliografici
Pubblicato in:Microorganisms
Autori principali: Bernatchez, Jean A., Chen, Emily, Hull, Mitchell V., McNamara, Case W., McKerrow, James H., Siqueira-Neto, Jair L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232187/
https://ncbi.nlm.nih.gov/pubmed/32224991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8040472
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