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Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease

Chagas' disease, caused by infection with the parasite Trypanosoma cruzi, is the major cause of heart failure in Latin America. Classic clinical manifestations result from the infection of heart muscle cells leading to progressive cardiomyopathy. To ameliorate disease, chemotherapy must eradica...

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Detalhes bibliográficos
Main Authors: Engel, Juan C., Ang, Kenny K. H., Chen, Steven, Arkin, Michelle R., McKerrow, James H., Doyle, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916317/
https://ncbi.nlm.nih.gov/pubmed/20547819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01777-09
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