Diverse Inhibitor Chemotypes Targeting Trypanosoma cruzi CYP51

BACKGROUND: Chagas Disease, a WHO- and NIH-designated neglected tropical disease, is endemic in Latin America and an emerging infection in North America and Europe as a result of population moves. Although a major cause of morbidity and mortality due to heart failure, as well as inflicting a heavy e...

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Autors principals: Gunatilleke, Shamila S., Calvet, Claudia M., Johnston, Jonathan B., Chen, Chiung-Kuang, Erenburg, Grigori, Gut, Jiri, Engel, Juan C., Ang, Kenny K. H., Mulvaney, Joseph, Chen, Steven, Arkin, Michelle R., McKerrow, James H., Podust, Larissa M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409115/
https://ncbi.nlm.nih.gov/pubmed/22860142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001736
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