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Cysteine Protease Inhibitors Cure an Experimental Trypanosoma cruzi Infection

Trypanosoma cruzi is the causative agent of Chagas' disease. The major protease, cruzain, is a target for the development of new chemotherapy. We report the first successful treatment of an animal model of Chagas' disease with inhibitors designed to inactivate cruzain. Treatment with fluor...

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Detalhes bibliográficos
Main Authors: Engel, Juan C., Doyle, Patricia S., Hsieh, Ivy, McKerrow, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213346/
https://ncbi.nlm.nih.gov/pubmed/9705954
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