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Cysteine protease inhibitors as chemotherapy: Lessons from a parasite target

Papain family cysteine proteases are key factors in the pathogenesis of cancer invasion, arthritis, osteoporosis, and microbial infections. Targeting this enzyme family is therefore one strategy in the development of new chemotherapy for a number of diseases. Little is known, however, about the effi...

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Main Authors: Selzer, Paul M., Pingel, Sabine, Hsieh, Ivy, Ugele, Bernhard, Chan, Victor J., Engel, Juan C., Bogyo, Matthew, Russell, David G., Sakanari, Judy A., McKerrow, James H.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC34234/
https://ncbi.nlm.nih.gov/pubmed/10500116
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