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Cysteine protease inhibitors as chemotherapy: Lessons from a parasite target

Papain family cysteine proteases are key factors in the pathogenesis of cancer invasion, arthritis, osteoporosis, and microbial infections. Targeting this enzyme family is therefore one strategy in the development of new chemotherapy for a number of diseases. Little is known, however, about the effi...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Selzer, Paul M., Pingel, Sabine, Hsieh, Ivy, Ugele, Bernhard, Chan, Victor J., Engel, Juan C., Bogyo, Matthew, Russell, David G., Sakanari, Judy A., McKerrow, James H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34234/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500116/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11015
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