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Cysteine protease inhibitors as chemotherapy: Lessons from a parasite target

Papain family cysteine proteases are key factors in the pathogenesis of cancer invasion, arthritis, osteoporosis, and microbial infections. Targeting this enzyme family is therefore one strategy in the development of new chemotherapy for a number of diseases. Little is known, however, about the effi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Selzer, Paul M., Pingel, Sabine, Hsieh, Ivy, Ugele, Bernhard, Chan, Victor J., Engel, Juan C., Bogyo, Matthew, Russell, David G., Sakanari, Judy A., McKerrow, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34234/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500116/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11015
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