Piecing together the FTO jigsaw

Por Frayling, Timothy M, Ong, Ken
Publicado em 2011

Recent progress in the use of genetics to understand links between type 2 diabetes and related metabolic traits

Por Yaghootkar, Hanieh, Frayling, Timothy M
Publicado em 2013

Parental diabetes and birthweight in 236 030 individuals in the UK Biobank Study

Por Tyrrell, Jessica S, Yaghootkar, Hanieh, Freathy, Rachel M, Hattersley, Andrew T, Frayling, Timothy M
Publicado em 2013

Genetic variants in Apolipoprotein AV alter triglyceride concentrations in pregnancy

Por Ward, Kirsten J, Shields, Beverley, Knight, Beatrice, Salzmann, Maurice B, Hattersley, Andrew T, Frayling, Timothy M
Publicado em 2003

The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI

Por Webster, Rebecca J, Warrington, Nicole M, Beilby, John P, Frayling, Timothy M, Palmer, Lyle J
Publicado em 2010

Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene

Por Ward, Kirsten J, Ellard, Sian, Yajnik, Chittaranjan S, Frayling, Timothy M, Hattersley, Andrew T, Venigalla, Prathyusha NS, Chandak, Giriraj R
Publicado em 2006

A study of association between common variation in the growth hormone-chorionic somatomammotropin hormone gene cluster and adult fasting insulin in a UK Caucasian population

Por Freathy, Rachel M, Mitchell, Simon MS, Knight, Beatrice, Shields, Beverley, Weedon, Michael N, Hattersley, Andrew T, Frayling, Timothy M
Publicado em 2006

Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach

Por Perry, John R.B., McCarthy, Mark I., Hattersley, Andrew T., Zeggini, Eleftheria, Weedon, Michael N., Frayling, Timothy M.
Publicado em 2009

Filaggrin gene mutations are associated with asthma and eczema in later life

Por Rice, Neil E., Patel, Bipen D., Lang, Iain A., Kumari, Meena, Frayling, Timothy M., Murray, Anna, Melzer, David
Publicado em 2008

FTO gene variation and measures of body mass in an African population

Por Hennig, Branwen J, Fulford, Anthony J, Sirugo, Giorgio, Rayco-Solon, Pura, Hattersley, Andrew T, Frayling, Timothy M, Prentice, Andrew M
Publicado em 2009

A Powerful Approach to Sub-Phenotype Analysis in Population-Based Genetic Association Studies

Por Morris, Andrew P, Lindgren, Cecilia M, Zeggini, Eleftheria, Timpson, Nicholas J, Frayling, Timothy M, Hattersley, Andrew T, McCarthy, Mark I
Publicado em 2010

The FTO/obesity associated locus and dietary intake in children

Por Timpson, Nicholas J, Emmett, Pauline M, Frayling, Timothy M, Rogers, Imogen, Hattersley, Andrew T, McCarthy, Mark I, Smith, George Davey
Publicado no Am J Clin Nutr (2008)

Low Frequency Variants in the Exons Only Encoding Isoform A of HNF1A Do Not Contribute to Susceptibility to Type 2 Diabetes

Por Jafar-Mohammadi, Bahram, Groves, Christopher J., Owen, Katharine R., Frayling, Timothy M., Hattersley, Andrew T., McCarthy, Mark I., Gloyn, Anna L.
Publicado em 2009

The Impact of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism on Severe Hypoglycemia in Type 2 Diabetes

Por Freathy, Rachel M., Lonnen, Kathryn F., Steele, Anna M., Minton, Jayne A. L., Frayling, Timothy M., Hattersley, Andrew T., MacLeod, Kenneth M.
Publicado em 2006

Genome-Wide Association Scan Allowing for Epistasis in Type 2 Diabetes

Por Bell, Jordana T., Timpson, Nicholas J., Rayner, N. William, Zeggini, Eleftheria, Frayling, Timothy M., Hattersley, Andrew T., Morris, Andrew P., McCarthy, Mark I.
Publicado em 2010

Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk

Por Lango, Hana, Palmer, Colin N.A., Morris, Andrew D., Zeggini, Eleftheria, Hattersley, Andrew T., McCarthy, Mark I., Frayling, Timothy M., Weedon, Michael N.
Publicado em 2008

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnanc...

Por Freathy, Rachel M., Ring, Susan M., Shields, Beverley, Galobardes, Bruna, Knight, Beatrice, Weedon, Michael N., Smith, George Davey, Frayling, Timothy M., Hattersley, Andrew T.
Publicado em 2009

Effects of the diabetes linked <it>TCF7L2 </it>polymorphism in a representative older population

Por Ferrucci Luigi, Corsi Anna, Bandinelli Stefania, Weedon Michael N, Hurst Alison J, Murray Anna, Melzer David, Paolisso Guiseppe, Guralnik Jack M, Frayling Timothy M
Publicado em 2006-12-01

The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians

Por Freathy, Rachel M, Weedon, Michael N, Melzer, David, Shields, Beverley, Hitman, Graham A, Walker, Mark, McCarthy, Mark I, Hattersley, Andrew T, Frayling, Timothy M
Publicado em 2006

Effects of the diabetes linked TCF7L2 polymorphism in a representative older population

Por Melzer, David, Murray, Anna, Hurst, Alison J, Weedon, Michael N, Bandinelli, Stefania, Corsi, Anna Maria, Ferrucci, Luigi, Paolisso, Guiseppe, Guralnik, Jack M, Frayling, Timothy M
Publicado em 2006