Parental diabetes and birthweight in 236 030 individuals in the UK Biobank Study

Por Tyrrell, Jessica S, Yaghootkar, Hanieh, Freathy, Rachel M, Hattersley, Andrew T, Frayling, Timothy M
Publicado em 2013

High Urinary Tungsten Concentration Is Associated with Stroke in the National Health and Nutrition Examination Survey 1999–2010

Por Tyrrell, Jessica, Galloway, Tamara S., Abo-Zaid, Ghada, Melzer, David, Depledge, Michael H., Osborne, Nicholas J.
Publicado em 2013

The Weather and Ménière’s Disease: A Longitudinal Analysis in the UK

Por Schmidt, Wiebke, Sarran, Christophe, Ronan, Natalie, Barrett, George, Whinney, David J., Fleming, Lora E., Osborne, Nicholas J., Tyrrell, Jessica
Publicado no Otol Neurotol (2017)

Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively

Por Wood, Andrew R., Tyrrell, Jessica, Beaumont, Robin, Jones, Samuel E., Tuke, Marcus A., Ruth, Katherine S., Yaghootkar, Hanieh, Freathy, Rachel M., Murray, Anna, Frayling, Timothy M., Weedon, Michael N.
Publicado no Diabetologia (2016)

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health

Por Ruth, Katherine S., Beaumont, Robin N., Tyrrell, Jessica, Jones, Samuel E., Tuke, Marcus A., Yaghootkar, Hanieh, Wood, Andrew R., Freathy, Rachel M., Weedon, Michael N., Frayling, Timothy M., Murray, Anna
Publicado no Hum Reprod (2016)

Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank

Por Tyrrell, Jessica, Jones, Samuel E, Beaumont, Robin, Astley, Christina M, Lovell, Rebecca, Yaghootkar, Hanieh, Tuke, Marcus, Ruth, Katherine S, Freathy, Rachel M, Hirschhorn, Joel N, Wood, Andrew R, Murray, Anna, Weedon, Michael N, Frayling, Timothy M
Publicado no BMJ (2016)

Gene–obesogenic environment interactions in the UK Biobank study

Por Tyrrell, Jessica, Wood, Andrew R, Ames, Ryan M, Yaghootkar, Hanieh, Beaumont, Robin N, Jones, Samuel E, Tuke, Marcus A, Ruth, Katherine S, Freathy, Rachel M, Davey Smith, George, Joost, Stéphane, Guessous, Idris, Murray, Anna, Strachan, David P, Kutalik, Zoltán, Weedon, Michael N, Frayling, Timothy M
Publicado no Int J Epidemiol (2017)

Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers

Por Pilling, Luke C., Atkins, Janice L., Duff, Michael O., Beaumont, Robin N., Jones, Samuel E., Tyrrell, Jessica, Kuo, Chia-Ling, Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Wood, Andrew R., Murray, Anna, Weedon, Michael N., Harries, Lorna W., Kuchel, George A., Ferrucci, Luigi, Frayling, Timothy M., Melzer, David
Publicado no PLoS One (2017)

Quantifying the extent to which index event biases influence large genetic association studies

Por Yaghootkar, Hanieh, Bancks, Michael P., Jones, Sam E., McDaid, Aaron, Beaumont, Robin, Donnelly, Louise, Wood, Andrew R., Campbell, Archie, Tyrrell, Jessica, Hocking, Lynne J., Tuke, Marcus A., Ruth, Katherine S., Pearson, Ewan R., Murray, Anna, Freathy, Rachel M., Munroe, Patricia B., Hayward, Caroline, Palmer, Colin, Weedon, Michael N., Pankow, James S., Frayling, Timothy M., Kutalik, Zoltán
Publicado no Hum Mol Genet (2017)

Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

Por Pilling, Luke C., Atkins, Janice L., Bowman, Kirsty, Jones, Samuel E., Tyrrell, Jessica, Beaumont, Robin N., Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Wood, Andrew R., Freathy, Rachel M., Murray, Anna, Weedon, Michael N., Xue, Luting, Lunetta, Kathryn, Murabito, Joanne M., Harries, Lorna W., Robine, Jean-Marie, Brayne, Carol, Kuchel, George A., Ferrucci, Luigi, Frayling, Timothy M., Melzer, David
Publicado no Aging (Albany NY) (2016)

Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

Por Yaghootkar, Hanieh, Lotta, Luca A., Tyrrell, Jessica, Smit, Roelof A. J., Jones, Sam E., Donnelly, Louise, Beaumont, Robin, Campbell, Archie, Tuke, Marcus A., Hayward, Caroline, Ruth, Katherine S., Padmanabhan, Sandosh, Jukema, J. Wouter, Palmer, Colin C., Hattersley, Andrew, Freathy, Rachel M., Langenberg, Claudia, Wareham, Nicholas J., Wood, Andrew R., Murray, Anna, Weedon, Michael N., Sattar, Naveed, Pearson, Ewan, Scott, Robert A., Frayling, Timothy M.
Publicado no Diabetes (2016)

A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

Por Frayling, Timothy M., Beaumont, Robin N., Jones, Samuel E., Yaghootkar, Hanieh, Tuke, Marcus A., Ruth, Katherine S., Casanova, Francesco, West, Ben, Locke, Jonathan, Sharp, Seth, Ji, Yingjie, Thompson, William, Harrison, Jamie, Etheridge, Amy S., Gallins, Paul J., Jima, Dereje, Wright, Fred, Zhou, Yihui, Innocenti, Federico, Lindgren, Cecilia M., Grarup, Niels, Murray, Anna, Freathy, Rachel M., Weedon, Michael N., Tyrrell, Jessica, Wood, Andrew R.
Publicado no Cell Rep (2018)

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

Por Jones, Samuel E., Tyrrell, Jessica, Wood, Andrew R., Beaumont, Robin N., Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Hu, Youna, Teder-Laving, Maris, Hayward, Caroline, Roenneberg, Till, Wilson, James F., Del Greco, Fabiola, Hicks, Andrew A., Shin, Chol, Yun, Chang-Ho, Lee, Seung Ku, Metspalu, Andres, Byrne, Enda M., Gehrman, Philip R., Tiemeier, Henning, Allebrandt, Karla V., Freathy, Rachel M., Murray, Anna, Hinds, David A., Frayling, Timothy M., Weedon, Michael N.
Publicado no PLoS Genet (2016)

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influen...

Por Tyrrell, Jessica, Huikari, Ville, Christie, Jennifer T., Cavadino, Alana, Bakker, Rachel, Brion, Marie-Jo A., Geller, Frank, Paternoster, Lavinia, Myhre, Ronny, Potter, Catherine, Johnson, Paul C.D., Ebrahim, Shah, Feenstra, Bjarke, Hartikainen, Anna-Liisa, Hattersley, Andrew T., Hofman, Albert, Kaakinen, Marika, Lowe, Lynn P., Magnus, Per, McConnachie, Alex, Melbye, Mads, Ng, Jane W.Y., Nohr, Ellen A., Power, Chris, Ring, Susan M., Sebert, Sylvain P., Sengpiel, Verena, Taal, H. Rob, Watt, Graham C.M., Sattar, Naveed, Relton, Caroline L., Jacobsson, Bo, Frayling, Timothy M., Sørensen, Thorkild I.A., Murray, Jeffrey C., Lawlor, Debbie A., Pennell, Craig E., Jaddoe, Vincent W.V., Hypponen, Elina, Lowe, William L., Jarvelin, Marjo-Riitta, Davey Smith, George, Freathy, Rachel M.
Publicado em 2012

Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers

Por Taylor, Amy E., Morris, Richard W., Fluharty, Meg E., Bjorngaard, Johan H., Åsvold, Bjørn Olav, Gabrielsen, Maiken E., Campbell, Archie, Marioni, Riccardo, Kumari, Meena, Hällfors, Jenni, Männistö, Satu, Marques-Vidal, Pedro, Kaakinen, Marika, Cavadino, Alana, Postmus, Iris, Husemoen, Lise Lotte N., Skaaby, Tea, Ahluwalia, Tarunveer S., Treur, Jorien L., Willemsen, Gonneke, Dale, Caroline, Wannamethee, S. Goya, Lahti, Jari, Palotie, Aarno, Räikkönen, Katri, Kisialiou, Aliaksei, McConnachie, Alex, Padmanabhan, Sandosh, Wong, Andrew, Dalgård, Christine, Paternoster, Lavinia, Ben-Shlomo, Yoav, Tyrrell, Jessica, Horwood, John, Fergusson, David M., Kennedy, Martin A., Frayling, Tim, Nohr, Ellen A., Christiansen, Lene, Ohm Kyvik, Kirsten, Kuh, Diana, Watt, Graham, Eriksson, Johan, Whincup, Peter H., Vink, Jacqueline M., Boomsma, Dorret I., Davey Smith, George, Lawlor, Debbie, Linneberg, Allan, Ford, Ian, Jukema, J. Wouter, Power, Christine, Hyppönen, Elina, Jarvelin, Marjo-Riitta, Preisig, Martin, Borodulin, Katja, Kaprio, Jaakko, Kivimaki, Mika, Smith, Blair H., Hayward, Caroline, Romundstad, Pål R., Sørensen, Thorkild I. A., Munafò, Marcus R., Sattar, Naveed
Publicado no PLoS Genet (2014)

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

Por Morris, Richard W, Taylor, Amy E, Fluharty, Meg E, Bjørngaard, Johan H, Åsvold, Bjørn Olav, Elvestad Gabrielsen, Maiken, Campbell, Archie, Marioni, Riccardo, Kumari, Meena, Korhonen, Tellervo, Männistö, Satu, Marques-Vidal, Pedro, Kaakinen, Marika, Cavadino, Alana, Postmus, Iris, Husemoen, Lise Lotte N, Skaaby, Tea, Ahluwalia, Tarun Veer Singh, Treur, Jorien L, Willemsen, Gonneke, Dale, Caroline, Wannamethee, S Goya, Lahti, Jari, Palotie, Aarno, Räikkönen, Katri, McConnachie, Alex, Padmanabhan, Sandosh, Wong, Andrew, Dalgård, Christine, Paternoster, Lavinia, Ben-Shlomo, Yoav, Tyrrell, Jessica, Horwood, John, Fergusson, David M, Kennedy, Martin A, Nohr, Ellen A, Christiansen, Lene, Kyvik, Kirsten Ohm, Kuh, Diana, Watt, Graham, Eriksson, Johan G, Whincup, Peter H, Vink, Jacqueline M, Boomsma, Dorret I, Davey Smith, George, Lawlor, Debbie, Linneberg, Allan, Ford, Ian, Jukema, J Wouter, Power, Chris, Hyppönen, Elina, Jarvelin, Marjo-Riitta, Preisig, Martin, Borodulin, Katja, Kaprio, Jaakko, Kivimaki, Mika, Smith, Blair H, Hayward, Caroline, Romundstad, Pål R, Sørensen, Thorkild I A, Munafò, Marcus R, Sattar, Naveed
Publicado no BMJ Open (2015)

Genetic evidence for causal relationships between maternal obesity-related traits and birth weight

Por Tyrrell, Jessica, Richmond, Rebecca C., Palmer, Tom M., Feenstra, Bjarke, Rangarajan, Janani, Metrustry, Sarah, Cavadino, Alana, Paternoster, Lavinia, Armstrong, Loren L., De Silva, N. Maneka G., Wood, Andrew R., Horikoshi, Momoko, Geller, Frank, Myhre, Ronny, Bradfield, Jonathan P., Kreiner-Møller, Eskil, Huikari, Ville, Painter, Jodie N., Hottenga, Jouke-Jan, Allard, Catherine, Berry, Diane J., Bouchard, Luigi, Das, Shikta, Evans, David M., Hakonarson, Hakon, Hayes, M. Geoffrey, Heikkinen, Jani, Hofman, Albert, Knight, Bridget, Lind, Penelope A., McCarthy, Mark I., McMahon, George, Medland, Sarah E., Melbye, Mads, Morris, Andrew P., Nodzenski, Michael, Reichetzeder, Christoph, Ring, Susan M., Sebert, Sylvain, Sengpiel, Verena, Sørensen, Thorkild I.A., Willemsen, Gonneke, de Geus, Eco J. C., Martin, Nicholas G., Spector, Tim D., Power, Christine, Järvelin, Marjo-Riitta, Bisgaard, Hans, Grant, Struan F.A., Nohr, Ellen A., Jaddoe, Vincent W., Jacobsson, Bo, Murray, Jeffrey C., Hocher, Berthold, Hattersley, Andrew T., Scholtens, Denise M., Smith, George Davey, Hivert, Marie-France, Felix, Janine F., Hyppönen, Elina, Lowe, William L., Frayling, Timothy M., Lawlor, Debbie A., Freathy, Rachel M.
Publicado no JAMA (2016)

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Por Beaumont, Robin N, Warrington, Nicole M, Cavadino, Alana, Tyrrell, Jessica, Nodzenski, Michael, Horikoshi, Momoko, Geller, Frank, Myhre, Ronny, Richmond, Rebecca C, Paternoster, Lavinia, Bradfield, Jonathan P, Kreiner-Møller, Eskil, Huikari, Ville, Metrustry, Sarah, Lunetta, Kathryn L, Painter, Jodie N, Hottenga, Jouke-Jan, Allard, Catherine, Barton, Sheila J, Espinosa, Ana, Marsh, Julie A, Potter, Catherine, Zhang, Ge, Ang, Wei, Berry, Diane J, Bouchard, Luigi, Das, Shikta, Hakonarson, Hakon, Heikkinen, Jani, Helgeland, Øyvind, Hocher, Berthold, Hofman, Albert, Inskip, Hazel M, Jones, Samuel E, Kogevinas, Manolis, Lind, Penelope A, Marullo, Letizia, Medland, Sarah E, Murray, Anna, Murray, Jeffrey C, Njølstad, Pål R, Nohr, Ellen A, Reichetzeder, Christoph, Ring, Susan M, Ruth, Katherine S, Santa-Marina, Loreto, Scholtens, Denise M, Sebert, Sylvain, Sengpiel, Verena, Tuke, Marcus A, Vaudel, Marc, Weedon, Michael N, Willemsen, Gonneke, Wood, Andrew R, Yaghootkar, Hanieh, Muglia, Louis J, Bartels, Meike, Relton, Caroline L, Pennell, Craig E, Chatzi, Leda, Estivill, Xavier, Holloway, John W, Boomsma, Dorret I, Montgomery, Grant W, Murabito, Joanne M, Spector, Tim D, Power, Christine, Järvelin, Marjo-Ritta, Bisgaard, Hans, Grant, Struan F A, Sørensen, Thorkild I A, Jaddoe, Vincent W, Jacobsson, Bo, Melbye, Mads, McCarthy, Mark I, Hattersley, Andrew T, Hayes, M Geoffrey, Frayling, Timothy M, Hivert, Marie-France, Felix, Janine F, Hyppönen, Elina, Lowe, William L, Evans, David M, Lawlor, Debbie A, Feenstra, Bjarke, Freathy, Rachel M
Publicado no Hum Mol Genet (2018)

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Por Macé, Aurélien, Tuke, Marcus A., Deelen, Patrick, Kristiansson, Kati, Mattsson, Hannele, Nõukas, Margit, Sapkota, Yadav, Schick, Ursula, Porcu, Eleonora, Rüeger, Sina, McDaid, Aaron F., Porteous, David, Winkler, Thomas W., Salvi, Erika, Shrine, Nick, Liu, Xueping, Ang, Wei Q., Zhang, Weihua, Feitosa, Mary F., Venturini, Cristina, van der Most, Peter J., Rosengren, Anders, Wood, Andrew R., Beaumont, Robin N., Jones, Samuel E., Ruth, Katherine S., Yaghootkar, Hanieh, Tyrrell, Jessica, Havulinna, Aki S., Boers, Harmen, Mägi, Reedik, Kriebel, Jennifer, Müller-Nurasyid, Martina, Perola, Markus, Nieminen, Markku, Lokki, Marja-Liisa, Kähönen, Mika, Viikari, Jorma S., Geller, Frank, Lahti, Jari, Palotie, Aarno, Koponen, Päivikki, Lundqvist, Annamari, Rissanen, Harri, Bottinger, Erwin P., Afaq, Saima, Wojczynski, Mary K., Lenzini, Petra, Nolte, Ilja M., Sparsø, Thomas, Schupf, Nicole, Christensen, Kaare, Perls, Thomas T., Newman, Anne B., Werge, Thomas, Snieder, Harold, Spector, Timothy D., Chambers, John C., Koskinen, Seppo, Melbye, Mads, Raitakari, Olli T., Lehtimäki, Terho, Tobin, Martin D., Wain, Louise V., Sinisalo, Juha, Peters, Annette, Meitinger, Thomas, Martin, Nicholas G., Wray, Naomi R., Montgomery, Grant W., Medland, Sarah E., Swertz, Morris A., Vartiainen, Erkki, Borodulin, Katja, Männistö, Satu, Murray, Anna, Bochud, Murielle, Jacquemont, Sébastien, Rivadeneira, Fernando, Hansen, Thomas F., Oldehinkel, Albertine J., Mangino, Massimo, Province, Michael A., Deloukas, Panos, Kooner, Jaspal S., Freathy, Rachel M., Pennell, Craig, Feenstra, Bjarke, Strachan, David P., Lettre, Guillaume, Hirschhorn, Joel, Cusi, Daniele, Heid, Iris M., Hayward, Caroline, Männik, Katrin, Beckmann, Jacques S., Loos, Ruth J. F., Nyholt, Dale R., Metspalu, Andres, Eriksson, Johan G., Weedon, Michael N., Salomaa, Veikko, Franke, Lude, Reymond, Alexandre, Frayling, Timothy M., Kutalik, Zoltán
Publicado no Nat Commun (2017)

Genome-wide associations for birth weight and correlations with adult disease

Por Horikoshi, Momoko, Beaumont, Robin N, Day, Felix R, Warrington, Nicole M, Kooijman, Marjolein N, Fernandez-Tajes, Juan, Feenstra, Bjarke, van Zuydam, Natalie R, Gaulton, Kyle J, Grarup, Niels, Bradfield, Jonathan P, Strachan, David P, Li-Gao, Ruifang, Ahluwalia, Tarunveer S, Kreiner, Eskil, Rueedi, Rico, Lyytikäinen, Leo-Pekka, Cousminer, Diana L, Wu, Ying, Thiering, Elisabeth, Wang, Carol A, Have, Christian T, Hottenga, Jouke-Jan, Vilor-Tejedor, Natalia, Joshi, Peter K, Boh, Eileen Tai Hui, Ntalla, Ioanna, Pitkänen, Niina, Mahajan, Anubha, van Leeuwen, Elisabeth M, Joro, Raimo, Lagou, Vasiliki, Nodzenski, Michael, Diver, Louise A, Zondervan, Krina T, Bustamante, Mariona, Marques-Vidal, Pedro, Mercader, Josep M, Bennett, Amanda J, Rahmioglu, Nilufer, Nyholt, Dale R, Ma, Ronald Ching Wan, Tam, Claudia Ha Ting, Tam, Wing Hung, Ganesh, Santhi K, van Rooij, Frank JA, Jones, Samuel E, Loh, Po-Ru, Ruth, Katherine S, Tuke, Marcus A, Tyrrell, Jessica, Wood, Andrew R, Yaghootkar, Hanieh, Scholtens, Denise M, Paternoster, Lavinia, Prokopenko, Inga, Kovacs, Peter, Atalay, Mustafa, Willems, Sara M, Panoutsopoulou, Kalliope, Wang, Xu, Carstensen, Lisbeth, Geller, Frank, Schraut, Katharina E, Murcia, Mario, van Beijsterveldt, Catharina EM, Willemsen, Gonneke, Appel, Emil V R, Fonvig, Cilius E, Trier, Caecilie, Tiesler, Carla MT, Standl, Marie, Kutalik, Zoltán, Bonas-Guarch, Sílvia, Hougaard, David M, Sánchez, Friman, Torrents, David, Waage, Johannes, Hollegaard, Mads V, de Haan, Hugoline G, Rosendaal, Frits R, Medina-Gomez, Carolina, Ring, Susan M, Hemani, Gibran, McMahon, George, Robertson, Neil R, Groves, Christopher J, Langenberg, Claudia, Luan, Jian'an, Scott, Robert A, Zhao, Jing Hua, Mentch, Frank D, MacKenzie, Scott M, Reynolds, Rebecca M, Lowe, William L, Tönjes, Anke, Stumvoll, Michael, Lindi, Virpi, Lakka, Timo A, van Duijn, Cornelia M, Kiess, Wieland, Körner, Antje, Sørensen, Thorkild IA, Niinikoski, Harri, Pahkala, Katja, Raitakari, Olli T, Zeggini, Eleftheria, Dedoussis, George V, Teo, Yik-Ying, Saw, Seang-Mei, Melbye, Mads, Campbell, Harry, Wilson, James F, Vrijheid, Martine, de Geus, Eco JCN, Boomsma, Dorret I, Kadarmideen, Haja N, Holm, Jens-Christian, Hansen, Torben, Sebert, Sylvain, Hattersley, Andrew T, Beilin, Lawrence J, Newnham, John P, Pennell, Craig E, Heinrich, Joachim, Adair, Linda S, Borja, Judith B, Mohlke, Karen L, Eriksson, Johan G, Widén, Elisabeth E, Kähönen, Mika, Viikari, Jorma S, Lehtimäki, Terho, Vollenweider, Peter, Bønnelykke, Klaus, Bisgaard, Hans, Mook-Kanamori, Dennis O, Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G, Pisinger, Charlotta, Pedersen, Oluf, Power, Christine, Hyppönen, Elina, Wareham, Nicholas J, Hakonarson, Hakon, Davies, Eleanor, Walker, Brian R, Jaddoe, Vincent WV, Jarvelin, Marjo-Riitta, Grant, Struan FA, Vaag, Allan A, Lawlor, Debbie A, Frayling, Timothy M, Davey Smith, George, Morris, Andrew P, Ong, Ken K, Felix, Janine F, Timpson, Nicholas J, Perry, John RB, Evans, David M, McCarthy, Mark I, Freathy, Rachel M
Publicado no Nature (2016)