Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight

Maternal smoking during pregnancy is associated with low birth weight. Common variation at rs1051730 is robustly associated with smoking quantity and was recently shown to influence smoking cessation during pregnancy, but its influence on birth weight is not clear. We aimed to investigate the associ...

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Detalhes bibliográficos
Main Authors: Tyrrell, Jessica, Huikari, Ville, Christie, Jennifer T., Cavadino, Alana, Bakker, Rachel, Brion, Marie-Jo A., Geller, Frank, Paternoster, Lavinia, Myhre, Ronny, Potter, Catherine, Johnson, Paul C.D., Ebrahim, Shah, Feenstra, Bjarke, Hartikainen, Anna-Liisa, Hattersley, Andrew T., Hofman, Albert, Kaakinen, Marika, Lowe, Lynn P., Magnus, Per, McConnachie, Alex, Melbye, Mads, Ng, Jane W.Y., Nohr, Ellen A., Power, Chris, Ring, Susan M., Sebert, Sylvain P., Sengpiel, Verena, Taal, H. Rob, Watt, Graham C.M., Sattar, Naveed, Relton, Caroline L., Jacobsson, Bo, Frayling, Timothy M., Sørensen, Thorkild I.A., Murray, Jeffrey C., Lawlor, Debbie A., Pennell, Craig E., Jaddoe, Vincent W.V., Hypponen, Elina, Lowe, William L., Jarvelin, Marjo-Riitta, Davey Smith, George, Freathy, Rachel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516066/
https://ncbi.nlm.nih.gov/pubmed/22956269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds372
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