The Impact of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism on Severe Hypoglycemia in Type 2 Diabetes

The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme gene (ACE) is associated with altered serum ACE activity. Raised ACE levels and the ACE DD genotype are associated with a 3.2 to 6.8-fold increased risk of severe hypoglycemia in type 1 diabetes. This relationship has not...

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Detalhes bibliográficos
Main Authors: Freathy, Rachel M., Lonnen, Kathryn F., Steele, Anna M., Minton, Jayne A. L., Frayling, Timothy M., Hattersley, Andrew T., MacLeod, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2006
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Original Data
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783578/
https://ncbi.nlm.nih.gov/pubmed/17487330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2006.3.76
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