Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene

Apolipoprotein AV (ApoAV) gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An MseI based RFLP analysis is the most commonly used method for genotyping this SNP. We genotyped a large cohort comprising 1185 Asian Indians and 173 UK Cauca...

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Detalhes bibliográficos
Main Authors: Ward, Kirsten J, Ellard, Sian, Yajnik, Chittaranjan S, Frayling, Timothy M, Hattersley, Andrew T, Venigalla, Prathyusha NS, Chandak, Giriraj R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513378/
https://ncbi.nlm.nih.gov/pubmed/16670016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-5-11
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