Glutamate racemase as a target for drug discovery

Por Fisher, Stewart L.
Publicado em 2008

Altered recognition mutants of the response regulator PhoB: A new genetic strategy for studying protein–protein interactions

Por Haldimann, Andreas, Prahalad, Murali K., Fisher, Stewart L., Kim, Soo-Ki, Walsh, Christopher T., Wanner, Barry L.
Publicado em 1996

A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy

Por Daryaee, Fereidoon, Zhang, Zhuo, Gogarty, Kayla R., Li, Yong, Merino, Jonathan, Fisher, Stewart L., Tonge, Peter J.
Publicado no Chem Sci (2017)

Secreted Gaussia princeps Luciferase as a Reporter of Escherichia coli Replication in a Mouse Tissue Cage Model of Infection

Por Liu, Mingyu, Blinn, Christina, McLeod, Sarah M., Wiseman, John W., Newman, Joseph V., Fisher, Stewart L., Walkup, Grant K.
Publicado em 2014

Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor

Por Ehmann, David E., Jahić, Haris, Ross, Philip L., Gu, Rong-Fang, Hu, Jun, Kern, Gunther, Walkup, Grant K., Fisher, Stewart L.
Publicado em 2012

Correlating drug–target kinetics and in vivo pharmacodynamics: long residence time inhibitors of the FabI enoyl-ACP reductase

Por Daryaee, Fereidoon, Chang, Andrew, Schiebel, Johannes, Lu, Yang, Zhang, Zhuo, Kapilashrami, Kanishk, Walker, Stephen G., Kisker, Caroline, Sotriffer, Christoph A., Fisher, Stewart L., Tonge, Peter J.
Publicado no Chem Sci (2016)

Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases

Por Ehmann, David E., Jahić, Haris, Ross, Philip L., Gu, Rong-Fang, Hu, Jun, Durand-Réville, Thomas F., Lahiri, Sushmita, Thresher, Jason, Livchak, Stephania, Gao, Ning, Palmer, Tiffany, Walkup, Grant K., Fisher, Stewart L.
Publicado em 2013

Conservation of the structure and function of bacterial tryptophan synthases

Por Michalska, Karolina, Gale, Jennifer, Joachimiak, Grazyna, Chang, Changsoo, Hatzos-Skintges, Catherine, Nocek, Boguslaw, Johnston, Stephen E., Bigelow, Lance, Bajrami, Besnik, Jedrzejczak, Robert P., Wellington, Samantha, Hung, Deborah T., Nag, Partha P., Fisher, Stewart L., Endres, Michael, Joachimiak, Andrzej
Publicado no IUCrJ (2019)

Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors

Por Fang, Chao, Lee, Katie K., Nietupski, Raymond, Bates, Robert H., Fernandez-Menendez, Raquel, Lopez-Roman, Eva Maria, Guijarro-Lopez, Laura, Yin, Yunxing, Peng, Zuozhong, Gomez, James E., Fisher, Stewart, Barros-Aguirre, David, Hubbard, Brian K., Serrano-Wu, Michael H., Hung, Deborah T.
Publicado no Bioorg Med Chem Lett (2018)

Translating slow-binding inhibition kinetics into cellular and in vivo effects

Por Walkup, Grant K., You, Zhiping, Ross, Philip L., Allen, Eleanor K. H., Daryaee, Fereidoon, Hale, Michael R., O’Donnell, John, Ehmann, David E., Schuck, Virna J. A., Buurman, Ed T., Choy, Allison L., Hajec, Laurel, Murphy-Benenato, Kerry, Marone, Valerie, Patey, Sara A., Grosser, Lena A., Johnstone, Michele, Walker, Stephen G., Tonge, Peter J., Fisher, Stewart L.
Publicado no Nat Chem Biol (2015)