A robust and quantitative method for tracking liposome contents after intravenous administration

door Kohli, Aditya G., Kieler-Ferguson, Heidi M., Chan, Darren, Szoka, Francis C.
Gepubliceerd in 2013

Hierarchical Particle Approach for Co-Precipitated Amorphous Solid Dispersions for Use in Preclinical In Vivo Studies

door Schenck, Luke, Boyce, Christopher, Frank, Derek, Koranne, Sampada, Ferguson, Heidi M., Strotman, Neil
Gepubliceerd in Pharmaceutics (2021)

Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids

door Kieler-Ferguson, Heidi M., Chan, Darren, Sockolosky, Jonathan, Finney, Lydia, Maxey, Evan, Vogt, Stefan, Szoka, Francis C.
Gepubliceerd in Eur J Pharm Sci (2017)

Design, Synthesis and Biological Evaluation of a Robust, Biodegradable Dendrimer

door van der Poll, Derek G., Kieler-Ferguson, Heidi M., Floyd, William C., Guillaudeu, Steven J., Jerger, Katherine, Szoka, Francis C., Fréchet, Jean M.
Gepubliceerd in 2010

The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice

door Umiker, Benjamin, Lee, Hyun-Hee, Cope, Julia, Ajami, Nadim J., Laine, Jean-Philippe, Fregeau, Christine, Ferguson, Heidi, Alves, Stephen E, Sciammetta, Nunzio, Kleinschek, Melanie, Salmon, Michael
Gepubliceerd in Innate Immun (2019)

Chemotherapeutic Evaluation of a Novel Synthetic Tubulysin Analogue-Dendrimer Conjugate in C26 Tumor Bearing Mice

door Floyd, William C., Datta, Gopal K., Imamura, Shinichi, Kieler-Ferguson, Heidi M., Jerger, Katherine, Patterson, Andrew W., Fox, Megan E., Szoka, Francis C., Fréchet, Jean M. J., Ellman, Jonathan A.
Gepubliceerd in 2011

Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors

door Pu, Qinglin, Zhang, Hongjun, Guo, Liangqin, Cheng, Mangeng, Doty, Amy C., Ferguson, Heidi, Fradera, Xavier, Lesburg, Charles A., McGowan, Meredeth A., Miller, J. Richard, Geda, Prasanthi, Song, Xuelei, Otte, Karin, Sciammetta, Nunzio, Solban, Nicolas, Yu, Wensheng, Sloman, David L., Zhou, Hua, Lammens, Alfred, Neumann, Lars, Bennett, David Jonathan, Pasternak, Alexander, Han, Yongxin
Gepubliceerd in ACS Med Chem Lett (2020)

Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy

door Zhang, Hongjun, Liu, Kun, Pu, Qinglin, Achab, Abdelghani, Ardolino, Michael J., Cheng, Mangeng, Deng, Yongqi, Doty, Amy C., Ferguson, Heidi, Fradera, Xavier, Knemeyer, Ian, Kurukulasuriya, Ravi, Lam, Yu-hong, Lesburg, Charles A., Martinot, Theodore A., McGowan, Meredeth A., Miller, J. Richard, Otte, Karin, Biju, Purakattle J., Sciammetta, Nunzio, Solban, Nicolas, Yu, Wensheng, Zhou, Hua, Wang, Xiao, Bennett, David Jonathan, Han, Yongxin
Gepubliceerd in ACS Med Chem Lett (2019)

Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases

door Zhang, Hongjun, Lapointe, Blair T., Anthony, Neville, Azevedo, Rita, Cals, Jos, Correll, Craig C., Daniels, Matthew, Deshmukh, Sujal, van Eenenaam, Hans, Ferguson, Heidi, Hegde, Laxminarayan G., Karstens, Willem Jan, Maclean, John, Miller, J. Richard, Moy, Lily Y., Simov, Vladimir, Nagpal, Sunil, Oubrie, Arthur, Palte, Rachel L., Parthasarathy, Gopal, Sciammetta, Nunzio, van der Stelt, Mario, Woodhouse, Janice D., Trotter, B. Wesley, Barr, Kenneth
Gepubliceerd in ACS Med Chem Lett (2020)

Combination of EP(4) antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells

door Wang, Yun, Cui, Long, Georgiev, Peter, Singh, Latika, Zheng, Yanyan, Yu, Ying, Grein, Jeff, Zhang, Chunsheng, Muise, Eric S., Sloman, David L., Ferguson, Heidi, Yu, Hongshi, Pierre, Cristina St., Dakle, Pranal J, Pucci, Vincenzo, Baker, James, Loboda, Andrey, Linn, Doug, Brynczka, Christopher, Wilson, Doug, Haines, Brian B, Long, Brian, Wnek, Richard, Sadekova, Svetlana, Rosenzweig, Michael, Haidle, Andrew, Han, Yongxin, Ranganath, Sheila H.
Gepubliceerd in Oncoimmunology (2021)

Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors

door Li, Derun, Deng, Yongqi, Achab, Abdelghani, Bharathan, Indu, Hopkins, Brett Andrew, Yu, Wensheng, Zhang, Hongjun, Sanyal, Sulagna, Pu, Qinglin, Zhou, Hua, Liu, Kun, Lim, Jongwon, Fradera, Xavier, Lesburg, Charles A., Lammens, Alfred, Martinot, Theodore A., Cohen, Ryan D., Doty, Amy C., Ferguson, Heidi, Nickbarg, Elliott B., Cheng, Mangeng, Spacciapoli, Peter, Geda, Prasanthi, Song, Xuelei, Smotrov, Nadya, Abeywickrema, Pravien, Andrews, Christine, Chamberlin, Chad, Mabrouk, Omar, Curran, Patrick, Richards, Matthew, Saradjian, Peter, Miller, J. Richard, Knemeyer, Ian, Otte, Karin M., Vincent, Stella, Sciammetta, Nunzio, Pasternak, Alexander, Bennett, David Jonathan, Han, Yongxin
Gepubliceerd in ACS Med Chem Lett (2021)