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A robust and quantitative method for tracking liposome contents after intravenous administration
We introduce a method for tracking the rate and extent of delivery of liposome contents in vivo based on encapsulation of 4-methylumbelliferyl phosphate (MU-P), a profluorophore of 4-methylumbelliferone (MU). MU-P is rapidly dephosphorylated by endogenous phosphatases in vivo to form MU after leakag...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040254/ https://ncbi.nlm.nih.gov/pubmed/24368300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.12.014 |
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