CFTR CFTR gene CFTR modulators CFTR variants CFTR-related disorders Cystic fibrosis MRSA Next Generation Sequencing (NGS) Staphylococcus aureus airway basal cell baculovirus bic Book Industry Communication::M Medicine biomarker common and new pathogenic variants cyclophosphamide cystic fibrosis disease liability drug development enterotoxin gene cluster ethnic Russian population exosomes functional assay gene therapy genotype-guided therapy genotype-phenotype correlations gut–lung axis health policies health policy human nasal epithelial cells incidence