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Mechanism of Alu integration into the human genome

LINE-1 or L1 has driven the generation of at least 10% of the human genome by mobilising Alu sequences. Although there is no doubt that Alu insertion is initiated by L1-dependent target site-primed reverse transcription, the mechanism by which the newly synthesised 3′ end of a given Alu cDNA attache...

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Autores principales: Chen, Jian-Min, Férec, Claude, Cooper, David N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276890/
https://ncbi.nlm.nih.gov/pubmed/18923924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11568-007-9002-9
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