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Searching for potential microRNA-binding site mutations amongst known disease-associated 3′ UTR variants

The 3′ untranslated regions (3′ UTRs) of human protein-coding genes play a pivotal role in the regulation of mRNA 3′ end formation, stability/degradation, nuclear export, subcellular localisation and translation, and hence are particularly rich in cis-acting regulatory elements. One recent addition...

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Detalhes bibliográficos
Main Authors: Chuzhanova, Nadia, Cooper, David N., Férec, Claude, Chen, Jian-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276887/
https://ncbi.nlm.nih.gov/pubmed/18923926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11568-006-9000-3
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