Regulators of homologous recombination repair as novel targets for cancer treatment

по Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Опубликовано в: Front Genet (2015)

Growth Differentiation Factor 15 (GDF-15) Plasma Levels Increase during Bleomycin- and Cisplatin-Based Treatment of Testicular Cancer Patients and Relate to Endothelial Damage

по Altena, Renske, Fehrmann, Rudolf S. N., Boer, Hink, de Vries, Elisabeth G. E., Meijer, Coby, Gietema, Jourik A.
Опубликовано в: PLoS One (2015)

Functional Genomic mRNA Profiling of a large cancer data base demonstrates mesothelin overexpression in a broad range of tumor types

по Lamberts, Laetitia E., de Groot, Derk Jan A., Bense, Rico D., de Vries, Elisabeth G.E., Fehrmann, Rudolf S.N.
Опубликовано в: Oncotarget (2015)

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

по Workel, Hagma H., van Rooij, Nienke, Plat, Annechien, Spierings, Diana C.J., Fehrmann, Rudolf S. N., Nijman, Hans W., de Bruyn, Marco
Опубликовано в: Int J Mol Sci (2020)

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy

по Steggink, Lars C., Boer, Hink, Meijer, Coby, Lefrandt, Joop D., Terstappen, Leon W. M. M., Fehrmann, Rudolf S. N., Gietema, Jourik A.
Опубликовано в: Pharmacogenomics J (2020)

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

по Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Опубликовано в: Nat Commun (2019)

Transcriptional effects of copy number alterations in a large set of human cancers

по Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Опубликовано в: Nat Commun (2020)

An mRNA expression-based signature for oncogene-induced replication-stress

по Llobet, Sergi Guerrero, Bhattacharya, Arkajyoti, Everts, Marieke, Kok, Klaas, van der Vegt, Bert, Fehrmann, Rudolf S.N., van Vugt, Marcel A.T.M.
Опубликовано в: Oncogene (2022)

Improving gene function predictions using independent transcriptional components

по Urzúa-Traslaviña, Carlos G., Leeuwenburgh, Vincent C., Bhattacharya, Arkajyoti, Loipfinger, Stefan, van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Fehrmann, Rudolf S. N.
Опубликовано в: Nat Commun (2021)

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

по Kok, Yannick P., Guerrero Llobet, Sergi, Schoonen, Pepijn M., Everts, Marieke, Bhattacharya, Arkajyoti, Fehrmann, Rudolf S. N., van den Tempel, Nathalie, van Vugt, Marcel A. T. M.
Опубликовано в: Oncogenesis (2020)

Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers

по Peters, Marloes A. M., Meijer, Coby, Fehrmann, Rudolf S. N., Walenkamp, Annemiek M. E., Kema, Ido P., de Vries, Elisabeth G. E., Hollema, Harry, Oosting, Sjoukje F.
Опубликовано в: Pathol Oncol Res (2019)

Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

по Brahm, Cyrillo G, Abdul, U Kulsoom, Houweling, Megan, van Linde, Myra E, Lagerweij, Tonny, Verheul, Henk M W, Westerman, Bart A, Walenkamp, Annemiek M E, Fehrmann, Rudolf S N
Опубликовано в: Neurooncol Adv (2020)

Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets

по Hartmans, Elmire, Orian-Rousseau, Veronique, Matzke-Ogi, Alexandra, Karrenbeld, Arend, de Groot, Derk Jan A., de Jong, Steven, van Dam, Gooitzen M., Fehrmann, Rudolf S.N., Nagengast, Wouter B.
Опубликовано в: Theranostics (2017)

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

по Bense, Rico D., Sotiriou, Christos, Piccart-Gebhart, Martine J., Haanen, John B. A. G., van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Schröder, Carolien P., Fehrmann, Rudolf S. N.
Опубликовано в: J Natl Cancer Inst (2016)

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

по van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Опубликовано в: Oncogene (2018)

Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approach

по de Jong, Mathilde R. W., Visser, Lydia, Huls, Gerwin, Diepstra, Arjan, van Vugt, Marcel, Ammatuna, Emanuele, van Rijn, Rozemarijn S., Vellenga, Edo, van den Berg, Anke, Fehrmann, Rudolf S. N., van Meerten, Tom
Опубликовано в: PLoS One (2018)

Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer

по Guerrero Llobet, Sergi, van der Vegt, Bert, Jongeneel, Evelien, Bense, Rico D., Zwager, Mieke C., Schröder, Carolien P., Everts, Marieke, Fehrmann, Rudolf S. N., de Bock, Geertruida H., van Vugt, Marcel A. T. M.
Опубликовано в: NPJ Breast Cancer (2020)

Clinical utility of circulating tumor DNA as a response and follow-up marker in cancer therapy

по Boonstra, Pieter A., Wind, Thijs T., van Kruchten, Michel, Schuuring, Ed, Hospers, Geke A. P., van der Wekken, Anthonie J., de Groot, Derk-Jan, Schröder, Carolien P., Fehrmann, Rudolf S. N., Reyners, Anna K. L.
Опубликовано в: Cancer Metastasis Rev (2020)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

по Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
Опубликовано 2013

Survival-Related Profile, Pathways, and Transcription Factors in Ovarian Cancer

по Crijns, Anne P. G, Fehrmann, Rudolf S. N, de Jong, Steven, Gerbens, Frans, Meersma, Gert Jan, Klip, Harry G, Hollema, Harry, Hofstra, Robert M. W, te Meerman, Gerard J., de Vries, Elisabeth G. E, van der Zee, Ate G. J
Опубликовано 2009