Regulators of homologous recombination repair as novel targets for cancer treatment

le Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Foilsithe in Front Genet (2015)

Growth Differentiation Factor 15 (GDF-15) Plasma Levels Increase during Bleomycin- and Cisplatin-Based Treatment of Testicular Cancer Patients and Relate to Endothelial Damage

le Altena, Renske, Fehrmann, Rudolf S. N., Boer, Hink, de Vries, Elisabeth G. E., Meijer, Coby, Gietema, Jourik A.
Foilsithe in PLoS One (2015)

Functional Genomic mRNA Profiling of a large cancer data base demonstrates mesothelin overexpression in a broad range of tumor types

le Lamberts, Laetitia E., de Groot, Derk Jan A., Bense, Rico D., de Vries, Elisabeth G.E., Fehrmann, Rudolf S.N.
Foilsithe in Oncotarget (2015)

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

le Workel, Hagma H., van Rooij, Nienke, Plat, Annechien, Spierings, Diana C.J., Fehrmann, Rudolf S. N., Nijman, Hans W., de Bruyn, Marco
Foilsithe in Int J Mol Sci (2020)

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy

le Steggink, Lars C., Boer, Hink, Meijer, Coby, Lefrandt, Joop D., Terstappen, Leon W. M. M., Fehrmann, Rudolf S. N., Gietema, Jourik A.
Foilsithe in Pharmacogenomics J (2020)

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

le Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Foilsithe in Nat Commun (2019)

Transcriptional effects of copy number alterations in a large set of human cancers

le Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Foilsithe in Nat Commun (2020)

An mRNA expression-based signature for oncogene-induced replication-stress

le Llobet, Sergi Guerrero, Bhattacharya, Arkajyoti, Everts, Marieke, Kok, Klaas, van der Vegt, Bert, Fehrmann, Rudolf S.N., van Vugt, Marcel A.T.M.
Foilsithe in Oncogene (2022)

Improving gene function predictions using independent transcriptional components

le Urzúa-Traslaviña, Carlos G., Leeuwenburgh, Vincent C., Bhattacharya, Arkajyoti, Loipfinger, Stefan, van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Fehrmann, Rudolf S. N.
Foilsithe in Nat Commun (2021)

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

le Kok, Yannick P., Guerrero Llobet, Sergi, Schoonen, Pepijn M., Everts, Marieke, Bhattacharya, Arkajyoti, Fehrmann, Rudolf S. N., van den Tempel, Nathalie, van Vugt, Marcel A. T. M.
Foilsithe in Oncogenesis (2020)

Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers

le Peters, Marloes A. M., Meijer, Coby, Fehrmann, Rudolf S. N., Walenkamp, Annemiek M. E., Kema, Ido P., de Vries, Elisabeth G. E., Hollema, Harry, Oosting, Sjoukje F.
Foilsithe in Pathol Oncol Res (2019)

Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

le Brahm, Cyrillo G, Abdul, U Kulsoom, Houweling, Megan, van Linde, Myra E, Lagerweij, Tonny, Verheul, Henk M W, Westerman, Bart A, Walenkamp, Annemiek M E, Fehrmann, Rudolf S N
Foilsithe in Neurooncol Adv (2020)

Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets

le Hartmans, Elmire, Orian-Rousseau, Veronique, Matzke-Ogi, Alexandra, Karrenbeld, Arend, de Groot, Derk Jan A., de Jong, Steven, van Dam, Gooitzen M., Fehrmann, Rudolf S.N., Nagengast, Wouter B.
Foilsithe in Theranostics (2017)

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

le Bense, Rico D., Sotiriou, Christos, Piccart-Gebhart, Martine J., Haanen, John B. A. G., van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Schröder, Carolien P., Fehrmann, Rudolf S. N.
Foilsithe in J Natl Cancer Inst (2016)

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

le van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Foilsithe in Oncogene (2018)

Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approach

le de Jong, Mathilde R. W., Visser, Lydia, Huls, Gerwin, Diepstra, Arjan, van Vugt, Marcel, Ammatuna, Emanuele, van Rijn, Rozemarijn S., Vellenga, Edo, van den Berg, Anke, Fehrmann, Rudolf S. N., van Meerten, Tom
Foilsithe in PLoS One (2018)

Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer

le Guerrero Llobet, Sergi, van der Vegt, Bert, Jongeneel, Evelien, Bense, Rico D., Zwager, Mieke C., Schröder, Carolien P., Everts, Marieke, Fehrmann, Rudolf S. N., de Bock, Geertruida H., van Vugt, Marcel A. T. M.
Foilsithe in NPJ Breast Cancer (2020)

Clinical utility of circulating tumor DNA as a response and follow-up marker in cancer therapy

le Boonstra, Pieter A., Wind, Thijs T., van Kruchten, Michel, Schuuring, Ed, Hospers, Geke A. P., van der Wekken, Anthonie J., de Groot, Derk-Jan, Schröder, Carolien P., Fehrmann, Rudolf S. N., Reyners, Anna K. L.
Foilsithe in Cancer Metastasis Rev (2020)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

le Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
Foilsithe 2013

Survival-Related Profile, Pathways, and Transcription Factors in Ovarian Cancer

le Crijns, Anne P. G, Fehrmann, Rudolf S. N, de Jong, Steven, Gerbens, Frans, Meersma, Gert Jan, Klip, Harry G, Hollema, Harry, Hofstra, Robert M. W, te Meerman, Gerard J., de Vries, Elisabeth G. E, van der Zee, Ate G. J
Foilsithe 2009