Regulators of homologous recombination repair as novel targets for cancer treatment

Tekijä Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Julkaisussa Front Genet (2015)

Growth Differentiation Factor 15 (GDF-15) Plasma Levels Increase during Bleomycin- and Cisplatin-Based Treatment of Testicular Cancer Patients and Relate to Endothelial Damage

Tekijä Altena, Renske, Fehrmann, Rudolf S. N., Boer, Hink, de Vries, Elisabeth G. E., Meijer, Coby, Gietema, Jourik A.
Julkaisussa PLoS One (2015)

Functional Genomic mRNA Profiling of a large cancer data base demonstrates mesothelin overexpression in a broad range of tumor types

Tekijä Lamberts, Laetitia E., de Groot, Derk Jan A., Bense, Rico D., de Vries, Elisabeth G.E., Fehrmann, Rudolf S.N.
Julkaisussa Oncotarget (2015)

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

Tekijä Workel, Hagma H., van Rooij, Nienke, Plat, Annechien, Spierings, Diana C.J., Fehrmann, Rudolf S. N., Nijman, Hans W., de Bruyn, Marco
Julkaisussa Int J Mol Sci (2020)

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy

Tekijä Steggink, Lars C., Boer, Hink, Meijer, Coby, Lefrandt, Joop D., Terstappen, Leon W. M. M., Fehrmann, Rudolf S. N., Gietema, Jourik A.
Julkaisussa Pharmacogenomics J (2020)

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

Tekijä Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Julkaisussa Nat Commun (2019)

Transcriptional effects of copy number alterations in a large set of human cancers

Tekijä Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Julkaisussa Nat Commun (2020)

An mRNA expression-based signature for oncogene-induced replication-stress

Tekijä Llobet, Sergi Guerrero, Bhattacharya, Arkajyoti, Everts, Marieke, Kok, Klaas, van der Vegt, Bert, Fehrmann, Rudolf S.N., van Vugt, Marcel A.T.M.
Julkaisussa Oncogene (2022)

Improving gene function predictions using independent transcriptional components

Tekijä Urzúa-Traslaviña, Carlos G., Leeuwenburgh, Vincent C., Bhattacharya, Arkajyoti, Loipfinger, Stefan, van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Fehrmann, Rudolf S. N.
Julkaisussa Nat Commun (2021)

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

Tekijä Kok, Yannick P., Guerrero Llobet, Sergi, Schoonen, Pepijn M., Everts, Marieke, Bhattacharya, Arkajyoti, Fehrmann, Rudolf S. N., van den Tempel, Nathalie, van Vugt, Marcel A. T. M.
Julkaisussa Oncogenesis (2020)

Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers

Tekijä Peters, Marloes A. M., Meijer, Coby, Fehrmann, Rudolf S. N., Walenkamp, Annemiek M. E., Kema, Ido P., de Vries, Elisabeth G. E., Hollema, Harry, Oosting, Sjoukje F.
Julkaisussa Pathol Oncol Res (2019)

Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

Tekijä Brahm, Cyrillo G, Abdul, U Kulsoom, Houweling, Megan, van Linde, Myra E, Lagerweij, Tonny, Verheul, Henk M W, Westerman, Bart A, Walenkamp, Annemiek M E, Fehrmann, Rudolf S N
Julkaisussa Neurooncol Adv (2020)

Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets

Tekijä Hartmans, Elmire, Orian-Rousseau, Veronique, Matzke-Ogi, Alexandra, Karrenbeld, Arend, de Groot, Derk Jan A., de Jong, Steven, van Dam, Gooitzen M., Fehrmann, Rudolf S.N., Nagengast, Wouter B.
Julkaisussa Theranostics (2017)

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

Tekijä Bense, Rico D., Sotiriou, Christos, Piccart-Gebhart, Martine J., Haanen, John B. A. G., van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Schröder, Carolien P., Fehrmann, Rudolf S. N.
Julkaisussa J Natl Cancer Inst (2016)

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

Tekijä van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Julkaisussa Oncogene (2018)

Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approach

Tekijä de Jong, Mathilde R. W., Visser, Lydia, Huls, Gerwin, Diepstra, Arjan, van Vugt, Marcel, Ammatuna, Emanuele, van Rijn, Rozemarijn S., Vellenga, Edo, van den Berg, Anke, Fehrmann, Rudolf S. N., van Meerten, Tom
Julkaisussa PLoS One (2018)

Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer

Tekijä Guerrero Llobet, Sergi, van der Vegt, Bert, Jongeneel, Evelien, Bense, Rico D., Zwager, Mieke C., Schröder, Carolien P., Everts, Marieke, Fehrmann, Rudolf S. N., de Bock, Geertruida H., van Vugt, Marcel A. T. M.
Julkaisussa NPJ Breast Cancer (2020)

Clinical utility of circulating tumor DNA as a response and follow-up marker in cancer therapy

Tekijä Boonstra, Pieter A., Wind, Thijs T., van Kruchten, Michel, Schuuring, Ed, Hospers, Geke A. P., van der Wekken, Anthonie J., de Groot, Derk-Jan, Schröder, Carolien P., Fehrmann, Rudolf S. N., Reyners, Anna K. L.
Julkaisussa Cancer Metastasis Rev (2020)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

Tekijä Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
Julkaistu 2013

Survival-Related Profile, Pathways, and Transcription Factors in Ovarian Cancer

Tekijä Crijns, Anne P. G, Fehrmann, Rudolf S. N, de Jong, Steven, Gerbens, Frans, Meersma, Gert Jan, Klip, Harry G, Hollema, Harry, Hofstra, Robert M. W, te Meerman, Gerard J., de Vries, Elisabeth G. E, van der Zee, Ate G. J
Julkaistu 2009