Indispensable benefit of independent investigator-driven research in a changing clinical trial landscape

by Oosting, Sjoukje F, Fehrmann, Rudolf S, de Vries, Elisabeth G E
Published in ESMO Open (2017)

Regulators of homologous recombination repair as novel targets for cancer treatment

by Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Published in Front Genet (2015)

Immune microenvironment composition in non‐small cell lung cancer and its association with survival

by Tamminga, Menno, Hiltermann, Thijo Jeroen N, Schuuring, Ed, Timens, Wim, Fehrmann, Rudolf SN, Groen, Harry JM
Published in Clin Transl Immunology (2020)

Growth Differentiation Factor 15 (GDF-15) Plasma Levels Increase during Bleomycin- and Cisplatin-Based Treatment of Testicular Cancer Patients and Relate to Endothelial Damage

by Altena, Renske, Fehrmann, Rudolf S. N., Boer, Hink, de Vries, Elisabeth G. E., Meijer, Coby, Gietema, Jourik A.
Published in PLoS One (2015)

Functional Genomic mRNA Profiling of a large cancer data base demonstrates mesothelin overexpression in a broad range of tumor types

by Lamberts, Laetitia E., de Groot, Derk Jan A., Bense, Rico D., de Vries, Elisabeth G.E., Fehrmann, Rudolf S.N.
Published in Oncotarget (2015)

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

by Workel, Hagma H., van Rooij, Nienke, Plat, Annechien, Spierings, Diana C.J., Fehrmann, Rudolf S. N., Nijman, Hans W., de Bruyn, Marco
Published in Int J Mol Sci (2020)

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy

by Steggink, Lars C., Boer, Hink, Meijer, Coby, Lefrandt, Joop D., Terstappen, Leon W. M. M., Fehrmann, Rudolf S. N., Gietema, Jourik A.
Published in Pharmacogenomics J (2020)

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

by Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Published in Nat Commun (2019)

MAPK pathway activity plays a key role in PD‐L1 expression of lung adenocarcinoma cells

by Stutvoet, Thijs S, Kol, Arjan, de Vries, Elisabeth GE, de Bruyn, Marco, Fehrmann, Rudolf SN, Terwisscha van Scheltinga, Anton GT, de Jong, Steven
Published in J Pathol (2019)

Transcriptional effects of copy number alterations in a large set of human cancers

by Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Published in Nat Commun (2020)

An mRNA expression-based signature for oncogene-induced replication-stress

by Llobet, Sergi Guerrero, Bhattacharya, Arkajyoti, Everts, Marieke, Kok, Klaas, van der Vegt, Bert, Fehrmann, Rudolf S.N., van Vugt, Marcel A.T.M.
Published in Oncogene (2022)

Improving gene function predictions using independent transcriptional components

by Urzúa-Traslaviña, Carlos G., Leeuwenburgh, Vincent C., Bhattacharya, Arkajyoti, Loipfinger, Stefan, van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Fehrmann, Rudolf S. N.
Published in Nat Commun (2021)

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

by Kok, Yannick P., Guerrero Llobet, Sergi, Schoonen, Pepijn M., Everts, Marieke, Bhattacharya, Arkajyoti, Fehrmann, Rudolf S. N., van den Tempel, Nathalie, van Vugt, Marcel A. T. M.
Published in Oncogenesis (2020)

Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers

by Peters, Marloes A. M., Meijer, Coby, Fehrmann, Rudolf S. N., Walenkamp, Annemiek M. E., Kema, Ido P., de Vries, Elisabeth G. E., Hollema, Harry, Oosting, Sjoukje F.
Published in Pathol Oncol Res (2019)

Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis

by He, Yuan, Bouwstra, Renee, Wiersma, Valerie R., de Jong, Mathilde, Jan Lourens, Harm, Fehrmann, Rudolf, de Bruyn, Marco, Ammatuna, Emanuele, Huls, Gerwin, van Meerten, Tom, Bremer, Edwin
Published in Nat Commun (2019)

Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

by Brahm, Cyrillo G, Abdul, U Kulsoom, Houweling, Megan, van Linde, Myra E, Lagerweij, Tonny, Verheul, Henk M W, Westerman, Bart A, Walenkamp, Annemiek M E, Fehrmann, Rudolf S N
Published in Neurooncol Adv (2020)

Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets

by Hartmans, Elmire, Orian-Rousseau, Veronique, Matzke-Ogi, Alexandra, Karrenbeld, Arend, de Groot, Derk Jan A., de Jong, Steven, van Dam, Gooitzen M., Fehrmann, Rudolf S.N., Nagengast, Wouter B.
Published in Theranostics (2017)

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

by Bense, Rico D., Sotiriou, Christos, Piccart-Gebhart, Martine J., Haanen, John B. A. G., van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Schröder, Carolien P., Fehrmann, Rudolf S. N.
Published in J Natl Cancer Inst (2016)

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

by van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Published in Oncogene (2018)

Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approach

by de Jong, Mathilde R. W., Visser, Lydia, Huls, Gerwin, Diepstra, Arjan, van Vugt, Marcel, Ammatuna, Emanuele, van Rijn, Rozemarijn S., Vellenga, Edo, van den Berg, Anke, Fehrmann, Rudolf S. N., van Meerten, Tom
Published in PLoS One (2018)